Results 11 to 20 of about 270,239 (265)

Caracterização do perfil auditivo de frentistas de postos de combustível

open access: yesAudiology: Communication Research, 2017
RESUMO Introdução Pesquisas voltadas para as populações com baixas exposições a solventes, ou exposições dentro dos níveis de tolerância permitidos em âmbito ocupacional ainda são restritas.
Fernanda Zucki   +5 more
doaj   +1 more source

Identification of gp96 as a novel target for treatment of autoimmune disease in mice. [PDF]

open access: yesPLoS ONE, 2010
Heat shock proteins have been implicated as endogenous activators for dendritic cells (DCs). Chronic expression of heat shock protein gp96 on cell surfaces induces significant DC activations and systemic lupus erythematosus (SLE)-like phenotypes in mice.
Jung Min Han   +7 more
doaj   +1 more source

Bisphenol A – Application, sources of exposure and potential risks in infants, children and pregnant women

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2015
Bisphenol A (BPA) is used in the chemical industry as a monomer in the production of plastics. It belongs to a group of compounds that disturb some of the functions of human body, the endocrine system in particular.
Karolina Mikołajewska   +2 more
doaj   +1 more source

Compound and Dose-Dependent Effects of Two Neonicotinoid Pesticides on Honey Bee (Apis mellifera) Metabolic Physiology

open access: yesInsects, 2019
Use of neonicotinoid pesticides is now ubiquitous, and consequently non-targeted arthropods are exposed to their residues at sub-lethal doses. Exposure to these neurotoxins may be a major contributor to poor honey bee colony health.
Steven C. Cook
doaj   +1 more source

Food contamination with acrylamide in terms of consumer health risk

open access: yesMedycyna Ogólna i Nauki o Zdrowiu, 2022
Introduction and objective Food is a basis for proper functioning of the human body. Inadequate quality of consumed food products may have a negative impact on mhuman health.
Agata Piekut   +3 more
doaj   +1 more source

A review of indoor Gaseous organic compounds and human chemical Exposure: Insights from Real-time measurements

open access: yesEnvironment International, 2022
Gaseous organic compounds, mainly volatile organic compounds (VOCs), have become a wide concern in various indoor environments where we spend the majority of our daily time. The sources, compositions, variations, and sinks of indoor VOCs are extremely complex, and their potential impacts on human health are less understood.
Bo You   +4 more
openaire   +3 more sources

Protocols for treating C. elegans with pharmacological agents, osmoles, and salts for imaging and behavioral assays

open access: yesSTAR Protocols, 2023
Summary: Research rigor can be enhanced by pairing genetic tools with pharmacology and manipulations of solutes or ions. Here, we present a protocol for treating C. elegans with pharmacological agents, osmoles, and salts. We describe steps for agar plate
Lei Wang, Bianca Graziano, Laura Bianchi
doaj   +1 more source

Advancing chemical safety assessment through an omics-based characterization of the test system-chemical interaction

open access: yesFrontiers in Toxicology, 2023
Assessing chemical safety is essential to evaluate the potential risks of chemical exposure to human health and the environment. Traditional methods relying on animal testing are being replaced by 3R (reduction, refinement, and replacement) principle ...
Giusy del Giudice   +47 more
doaj   +1 more source

Biodegradation of mycotoxins: Tales from known and unexplored worlds

open access: yesFrontiers in Microbiology, 2016
Exposure to mycotoxins, secondary metabolites produced by fungi, may infer serious risks for animal and human health and lead to economic losses. Several approaches to reduce these mycotoxins have been investigated such as chemical removal, physical ...
Ilse eVanhoutte   +2 more
doaj   +1 more source

Metabolic stability and its role in the discovery of new chemical entities

open access: yesActa Pharmaceutica, 2019
Determination of metabolic profiles of new chemical entities is a key step in the process of drug discovery, since it influences pharmacokinetic characteristics of therapeutic compounds.
Słoczyńska Karolina   +6 more
doaj   +1 more source

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