Results 91 to 100 of about 9,815,687 (260)

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

open access: yesAdvanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger   +5 more
wiley   +1 more source

Trends in harmful drug exposure during pregnancy in France between 2013 and 2019: A nationwide cohort study.

open access: yesPLoS ONE
ObjectiveDescribe the trends of exposure to harmful drugs during pregnancy over recent years in France.DesignNationwide cohort study.SettingThe French National administrative health Data System (SNDS).PopulationPregnancies starting between 2013 and 2019 ...
Margaux Louchet   +6 more
doaj   +1 more source

An International Harmful Algal Information System (HAIS)

open access: yes, 2009
This document describes the vision, structure and partnerships for an international information system on the occurrence, impacts, identification, and monitoring of marine and brackish water planktonic and benthic microalgae perceived as harmful by ...

core  

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

open access: yesAdvanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli   +8 more
wiley   +1 more source

LEAD: Literature Enhanced Ab Initio Discovery of Nitride Dusting Layers for Enhanced Tunnel Magnetoresistance and Lower Resistance Magnetic Tunnel Junctions

open access: yesAdvanced Materials, EarlyView.
Magnetic tunnel junctions (MTJs) using MgO tunnel barriers face challenges of high resistance‐area product and low tunnel magnetoresistance (TMR). To discover alternative materials, Literature Enhanced Ab initio Discovery (LEAD) is developed. The LEAD‐predicted materials are theoretically evaluated, showing that MTJs with dusting of ScN or TiN on ...
Sabiq Islam   +6 more
wiley   +1 more source

Adopting an Ecological Health Model to Harmful Alcohol Use in Nigeria’s Niger Delta

open access: yesEuropean Journal of Mental Health, 2018
Substance abuse has ravaged potentials and keeps clamping down on the stability of societies. It is increasingly becoming a social problem that demands sustainable remedies, particularly in Nigeria’s Niger Delta.
Prince Agwu   +4 more
doaj  

The Barriers and Enablers of Co-design for Services [PDF]

open access: yes, 2016
As interest towards co-design for services in the public sector and in companies is growing, the benefits and challenges of applying it in organisations have become a topical issue.
Pirinen, Antti
core  

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

open access: yesAdvanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena   +3 more
wiley   +1 more source

ECONOMIA ZONELOR TRANSFRONTALIERE

open access: yesStudia Universitatis Moldaviae: Stiinte Umanistice, 2009
The flexibility achieved by off-shore companies as a vehicle for tax, financial and commercial planning, both for commercial and individual issues, has increased the volume and complexity of transactions channeled through these companies, based on
ADMIN ADMIN
doaj  

Home - About - Disclaimer - Privacy