Results 41 to 50 of about 141,907 (269)
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Impact of Multiple Grid-Connected Solar PV Inverters on Harmonics in the High-Frequency Range
EnergiesIn recent years, integration of solar photovoltaic (PV) systems into distribution networks has been increasing rapidly, as it has become the most promising renewable energy source (RES) in the transition of power generation from centralised to ...
Kasun Peiris +3 more
doaj +1 more source
Harmonic Oscillators in CMOS—A Tutorial Overview
IEEE Open Journal of the Solid-State Circuits Society, 2021 The harmonic oscillator is a truly irreplaceable as well as ubiquitous analog integrated circuit. Starting from the basics of its CMOS implementation, we will discuss the phase noise of the harmonic oscillator in some detail, where the intrinsic large ...
Pietro Andreani, Andrea Bevilacqua
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Gambus Hadhramaut: The Malaysian Malay Lute Tuning Retrieval
BioResources, 2023 This study identified elements in a simple homemade gambus from a local crafter using a scientific approach. The gambus was made from geronggang wood (Cratoxylum arborescens), a light Malaysian hardwood with pink sapwood, distinct from the heartwood with
Sinin Hamdan +4 more
doaj