Results 41 to 50 of about 1,011,636 (279)

Leveraging multiple data types for improved compound-kinase bioactivity prediction

open access: yesNature Communications
Machine learning provides efficient ways to map compound-kinase interactions. However, diverse bioactivity data types, including single-dose and multi-dose-response assay results, present challenges.
Ryan Theisen   +4 more
doaj   +1 more source

ADELIC HARMONIC OSCILLATOR [PDF]

open access: yesInternational Journal of Modern Physics A, 1995
Using the Weyl quantization we formulate one-dimensional adelic quantum mechanics, which unifies and treats ordinary and p-adic quantum mechanics on an equal footing. As an illustration the corresponding harmonic oscillator is considered. It is a simple, exact and instructive adelic model. Eigenstates are Schwartz-Bruhat functions.
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Capturing Long-Range Dependence and Harmonic Phenomena in 24-Hour Solar Irradiance Forecasting: A Quantile Regression Robustification via Forecasts Combination Approach

open access: yesIEEE Access, 2020
The global horizontal irradiance data recorded at the earth's horizontal surface is a mixture of deterministic (extra-terrestrially) and stochastic components due to the ever-changing atmospheric conditions. The Box-Jenkins short memory stochastic models
Edmore Ranganai, Caston Sigauke
doaj   +1 more source

Harmonic conjugation in harmonic matroids

open access: yesDiscrete Mathematics, 2009
This paper was finished in 2008.
openaire   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Analysis of Energy Transport Behavior and Geometric Effects in Graphene

open access: yesFrontiers in Mechanical Engineering, 2020
Graphene is an excellent heat conductor, with the potential to be used as a heat spreader for applications where there are fast, transient heat pulses.
Alejandro Guajardo-Cuéllar   +3 more
doaj   +1 more source

Harmonic and relative harmonic dimensions

open access: yesAnnales Academiae Scientiarum Fennicae. Series A. I. Mathematica, 1985
On an open Riemann surface R of Heins type (i.e. R is parabolic with a single ideal boundary component, \(\delta\) R), this paper considers the relationship between the harmonic dimension of the ideal boundary, dim \(\delta\) R, and the relative harmonic dimension of the ideal boundary, \(\dim_ F\delta R\).
Nakai, Mitsuru, Sario, Leo
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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