Results 61 to 70 of about 348,565 (319)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Harmonic Alignment [PDF]

, 2020
Published in SIAM Data Mining 2020.
Jay S. Stanley III, Scott Gigante, Guy Wolf, Smita Krishnaswamy   +3 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Impact of Multiple Grid-Connected Solar PV Inverters on Harmonics in the High-Frequency Range

Energies
In recent years, integration of solar photovoltaic (PV) systems into distribution networks has been increasing rapidly, as it has become the most promising renewable energy source (RES) in the transition of power generation from centralised to ...
Kasun Peiris, Sean Elphick, Jason David, Duane Robinson   +3 more
doaj   +1 more source

Harmonic Oscillators in CMOS—A Tutorial Overview

IEEE Open Journal of the Solid-State Circuits Society, 2021
The harmonic oscillator is a truly irreplaceable as well as ubiquitous analog integrated circuit. Starting from the basics of its CMOS implementation, we will discuss the phase noise of the harmonic oscillator in some detail, where the intrinsic large ...
Pietro Andreani, Andrea Bevilacqua
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Multiple sets of solutions for harmonic elimination PWM bipolar waveforms: Analysis and experimental verification

, 2006
Multiple sets of solutions for the selective harmonic elimination pulse-width modulation method for inverter control exist. These sets present an independent solution to the same problem but further investigation reveals that certain sets may offer an ...
Agelidis, VG, Balouktsis, A, Cossar, C, Cossar, C., Balouktsis, A., Balouktsis, I, Agelidis, V.G., Balouktsis, I.   +7 more
core   +1 more source

Gambus Hadhramaut: The Malaysian Malay Lute Tuning Retrieval

BioResources, 2023
This study identified elements in a simple homemade gambus from a local crafter using a scientific approach. The gambus was made from geronggang wood (Cratoxylum arborescens), a light Malaysian hardwood with pink sapwood, distinct from the heartwood with
Sinin Hamdan, Khairul Anwar Mohamad Said, Md. Rezaur Rahman, Marini Sawawi, Aaliyawani Ezzerin Sinin   +4 more
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Harmonic maps, SU (N) skyrme models and yang-mills theories [PDF]

, 2002
This thesis examines the construction of static solutions of (3+l)-dimensional SU{N) Skyrme models, usual and alternative, and pure massive SU(N) Yang-Mills theories.
Wospakrik, Hans Jacobus
core