Results 81 to 90 of about 141,907 (269)
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Nakai, Mitsuru, Sario, Leo
openaire +2 more sources
![Figure][1] When musicians harmonize, whether they are a barbershop quartet, the Beach Boys, or a symphony orchestra, the effectiveness is clear. We are now in an era in which effectiveness is a major goal of medical care delivery.
openaire +2 more sources
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Using all-phase Fourier method to reconstruct discontinuous signal
In order to reconstruct discontinuous signal with the least error by using finite information, the concept of all-phase data processing and the conventional Fourier approximation were combined.
HUANG Xiang-dong +2 more
doaj
Study on the Fast Replacement Mode of Payload and Its Vibration Characteristics
The existing payload has an urgent needs to shorten the maintenance time in technical requirements. This paper offered a new type of payload fast replacement mode.
ZHANG Yuan, MENG Bo-yang, JIANG Xiao-han
doaj +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Using a theorem of \textit{S. J. Gardiner} [Harmonic approximation (1995; Zbl 0826.31002)], the author shows that there exists a harmonic function \(h\) on a non-empty open subset \(\Omega\) of \(\mathbb{R}^d\), where \(d\geq 2\), which behaves wildly near every boundary point of \(\Omega\).
openaire +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source

