Results 51 to 60 of about 5,501,393 (253)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Stability criteria for delay differential-algebraic equations

open access: yes上海师范大学学报. 自然科学版, 2014
The asymptotic stability of delay differential-algebraic equations are researched in this paper.Two stability criteria described by evaluating a corresponding harmonic function on the boundary of a torus region are presented.
LIU Lingling, FAN Ni, SUN Leping
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Some Remarks on Harmonic Functions in Minkowski Spaces

open access: yesMathematics, 2019
We prove that in Minkowski spaces, a harmonic function does not necessarily satisfy the mean value formula. Conversely, we also show that a function satisfying the mean value formula is not necessarily a harmonic function.
Songting Yin
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Large signal 2nd harmonic on wafer MESFET characterization [PDF]

open access: yes, 1990
An automatic test set which performs a real time harmonic load-pull characterization is proposed. An active load technique is used in order to set the load at the test frequency and its harmonics and a complete set of device parameters useful for power ...
Andrea Ferrero   +4 more
core   +1 more source

Stability criteria for neutral delay differential-algebraic equations

open access: yes上海师范大学学报. 自然科学版, 2013
The asymptotic stability of neutral delay differential-algebraic equations is studied in this paper.Two stability criteria described by evaluating a corresponding harmonic function on the boundary of a torus region are presented.
FAN Ni, LIU Lingling, SUN Leping
doaj  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

On the analytical part of harmonic univalent functions defined by generalized SA˘LA˘GEAN Drivatives [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2009
In the present paper and by making use the generalized S.al.agean derivatives we have introduce and study a class of analytic function and prove the coefficient conditions, distortion bound, fractional integral operator, convex combination, and radius of
doaj   +1 more source

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