Results 51 to 60 of about 140,378 (296)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Novel Voltage Sag Detection Method Based on a Selective Harmonic Extraction Algorithm for Nonideal Grid Conditions

open access: yesEnergies, 2022
Voltage sag detection is utilized to capture the sag occurrence moment and calculate the sag depth of power grid voltage in real time, so as to generate reference voltage for controlling voltage interactive equipment such as dynamic voltage restorers ...
Zhenyu Li   +4 more
doaj   +1 more source

VUV frequency combs from below-threshold harmonics [PDF]

open access: yes, 2009
Recent demonstrations of high-harmonic generation (HHG) at very high repetition frequencies (~100 MHz) may allow for the revolutionary transfer of frequency combs to the vacuum ultraviolet (VUV).
A Marian   +37 more
core   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Development of Harmonic Drive Combining Four Arcs for Conventional Kinematic Application

open access: yesMachines, 2022
This paper proposes a modified harmonic cam, which is used to design a harmonic drive. Conventional harmonic drives using a sinusoidal cam type pertain to an elastic body concept and are thus difficult to design and evaluate.
Taesu Kim   +4 more
doaj   +1 more source

A Blind Interference Canceling Technique for Two-Stage Harmonic Rejection in Down-mixers [PDF]

open access: yes, 2008
This paper presents practical experiments on a harmonic rejection down-mixer, which offers up to 75 dB of harmonic rejection, without an RF filter. The down-mixer uses a two-stage approach; the first stage is an analog multi-path/multiphase harmonic ...
Klumperink, E.A.M.   +2 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Adaptable Bandwidth for Harmonic Step-Frequency Radar

open access: yesInternational Journal of Antennas and Propagation, 2015
A spectrum sensing technique is described which is used to enhance the performance of harmonic step-frequency radar in the presence of harmful radio frequency (RF) interference (RFI). This technique passively monitors the RF spectrum for subbands of high
Anthony F. Martone   +6 more
doaj   +1 more source

Efficiency of adaptive filter with envelope tracking algorithm when receiving signals with multi-position PSK against the background of non-fluctuation interferences

open access: yesРоссийский технологический журнал, 2020
The energy and spectral advantages of signals with phase-shift keying predetermined their widespread use in modern digital navigation, communications and television systems.
G. V. Kulikov, Trung Tien Do
doaj   +1 more source

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