Results 71 to 80 of about 214,301 (272)
Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source
Implementation of Harmonic Mapping to a Cloak Phenomenon
In this work, a novel physical transformation-based approach has been employed to realize the cloak effect. The transformation mapping is derived for the first time by minimizing the energy functional subject to specified geometric constraints on the ...
Najma Abdul Rehman +3 more
doaj +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Some results and examples of the biharmonic maps with potential
In this paper, we will study the class of biharmonic maps with potential, in the particular case represented by conformal maps between equidimensional manifolds. Some examples are constructed in particular cases (Euclidean space and sphere).
Abdelkader Zagane, Seddik Ouakkas
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
On the stability of harmonic maps under the homogeneous Ricci flow
In this work we study properties of stability and non-stability of harmonic maps under the homogeneous Ricci flow.We provide examples where the stability (non-stability) is preserved under the Ricci flow and an example where the Ricci flow does not ...
Prado Rafaela F. do, Grama Lino
doaj +1 more source
Artifacts reduction in strain maps of tagged magnetic resonance imaging using harmonic phase
Tagged Magnetic Resonance Imaging (MRI) is a noninvasive technique for examining myocardial function and deformation. Tagged MRI can also be used in quasistatic MR elastography to acquire strain maps of other biological soft tissues. Harmonic phase (HARP)
Wang Daolei +2 more
doaj +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source

