Results 201 to 210 of about 81,520 (260)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Listening to MS: AI-assisted speech analysis for diagnosis and fatigue prediction (COMMITMENT). [PDF]

Front Digit Health
Hammer H, Gonzalez-Machorro M, Hecker P, Reichel U, Zmutt A, Pedrotti L, Chan A, Eyben F, Sagha H, Kahlau M, Arnrich B, Schuller BW, Hoepner R.   +12 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Deciphering Infrared Difference Spectra of Bovine Rhodopsin in the Amide I Region by Localized Anharmonic Vibrational Calculations. [PDF]

J Phys Chem B
Matsuyama N, Katayama K, Yagi K.
europepmc   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

A transverse picoNewton force revealed in anisotropic Womersley flow. [PDF]

Sci Rep
Saqr KM.
europepmc   +1 more source

Auditory perception and neural representation of temporal features are altered by age but not by cochlear synaptopathy. [PDF]

Elife
Steenken F, Beutelmann R, Oetjen H, Köppl C, Klump GM.   +4 more
europepmc   +1 more source

Outcome of HARMONIC Shears for lower limb free flap reconstruction in trauma: A retrospective cohort study. [PDF]

JPRAS Open
Nishijo M, Jaibaji R, Pang C, Loh CYY.
europepmc   +1 more source

Harmonic and power spectrum analysis of vertical ground reaction force in patients who have a stroke within 3 months. [PDF]

Exp Physiol
Zhang L, Yao H, Fu S, Chien JH.
europepmc   +1 more source