Results 81 to 90 of about 475,497 (278)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Crystalline boson phases in harmonic traps: Beyond the Gross-Pitaevskii mean field

open access: yes, 2004
Strongly repelling bosons in two-dimensional harmonic traps are described through breaking of rotational symmetry at the Hartree-Fock level and subsequent symmetry restoration via projection techniques, thus incorporating correlations beyond the Gross ...
Constantine Yannouleas   +5 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Prevalence-Insensitive Evaluation of Diagnostic Systems Under Class Imbalance: The Harmonic Mean of Per-Class Sensitivity

open access: yesMathematics
In safety-critical diagnosis under class imbalance, widely used global metrics—e.g., accuracy, F-score, and MCC—conflate class-conditional behavior with class priors, often yielding overly optimistic assessments of overall performance, thereby hindering ...
Jesús S. Aguilar-Ruiz
doaj   +1 more source

Dois critérios de seleção na pré- desmama em bovinos da raça Gir. 2. Efeito na classificação dos animais Two pre-weaning selection criteria in Gyr cattle. 2. Effect in animal classification

open access: yesRevista Brasileira de Zootecnia, 2005
A utilização de dois critérios de seleção na pré-desmama, ganho médio diário do nascimento à desmama (GMD) e dias para ganhar 160 kg do nascimento à desmama (D160), foi estudada, analisando-se informações de 16.592 animais, provenientes do controle de ...
Carolina Amália de Souza Dantas Muniz   +3 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Sharp bounds for the Sándor–Yang means in terms of arithmetic and contra-harmonic means

open access: yesJournal of Inequalities and Applications, 2018
In the article, we provide several sharp upper and lower bounds for two Sándor–Yang means in terms of combinations of arithmetic and contra-harmonic means.
Hui-Zuo Xu, Yu-Ming Chu, Wei-Mao Qian
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

A FRAMEWORK FOR MORPHOLOGICAL OPERATIONS USING COUNTER HARMONIC MEAN [PDF]

open access: yesProceedings on Engineering Sciences
In this article, we have a tendency to embrace a novel framework for learning morphological operations using counter-harmonic mean. It combines the conception of morphology with convolutional neural networks.
Savya Sachi   +7 more
doaj   +1 more source

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