Results 41 to 50 of about 3,899 (265)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Analysis of the Impact of Volt/VAR Control on Harmonics Content and Alternative Harmonic Mitigation Methods

Energies
This article presents information about harmonic distortion and resonance in distribution networks. The theory behind harmonics and resonance is presented. Examples from the literature and the results of power quality measurements, as well as the authors’
Krzysztof Lowczowski, Jaroslaw Gielniak, Zbigniew Nadolny, Magdalena Udzik   +3 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Harmonic mitigation for symmetrical cascaded h-bridge inverter using sparrow search algorithm

Journal of Electrical Systems and Information Technology
Harmonics in multilevel inverters (MLIs) pose a critical challenge in power electronic systems, degrading power quality and complicating compliance with grid standards.
Daniel Igenumah Tennyson, Abdussamad Umar Jibia, Ibrahim Haruna Shanono, Nasiru Bello Kadandani   +3 more
doaj   +1 more source

A meta‐heuristic capacitor placement framework for distribution grids using modal resonance analysis

IET Renewable Power Generation, 2022
Shunt capacitors are usually installed in distribution grids for power factor correction. On the other hand, the number of harmonic‐producing sources such as wind turbines (WTs), photovoltaic (PV) panels, storage units, and electronic loads is rapidly ...
Hossein Farzin, Mehdi Monadi
doaj   +1 more source

Rod Origami (RodOri) Spring Metamaterials for Tunable Vibration Control via Tailored Structural Instabilities. [PDF]

Adv Sci (Weinh)
Rod Origami (RodOri) springs harness snap‐through instabilities of pre‐stressed curved rods with geometrically programmable buckling behavior. Integrating RodOri springs with distinct geometries yields multistable metamaterials that undergo stepwise reconfiguration via sequential snapping, achieving wide‐range tunability of stiffness and resonance ...
Lee J, Leanza S, Zhao RR.
europepmc   +2 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Harmonic distortion in power systems due to electronic control and renewable energy integration: a comprehensive review

Discover Electronics
The present manuscript offers a detailed review of literature about the harmonic distortion causes and mitigation methods in modern electrical power systems.
Jagdeep Kaur, Sarbjeet Kaur Bath
doaj   +1 more source

A harmonic suppression strategy based on harmonic impedance reshaping of grid-forming converters

Zhejiang dianli
With the large-scale integration of nonlinear loads and power electronic equipment into power systems， voltage distortion at the point of common coupling （PCC） has become increasingly prominent， severely affecting power quality and the safe and stable ...
WANG Kangping, ZHI Yuan, GE Pengjiang, LYU Jinli   +3 more
doaj   +1 more source