Results 41 to 50 of about 351,945 (274)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Harmonic Numbers: Insights, Approximations and Applications

open access: yesSpreadsheets in Education, 2015
The applications of spreadsheets to mathematics allow learners to analyze mathematical ideas in ways never before possible. In this paper harmonic numbers are defined, calculated, approximated, and applied.
John A Rochowicz
doaj   +2 more sources

Identities between harmonic, hyperharmonic and Daehee numbers

open access: yesJournal of Inequalities and Applications, 2018
In this paper, we present some identities relating the hyperharmonic, the Daehee and the derangement numbers, and we derive some nonlinear differential equations from the generating function of a hyperharmonic number.
Seog-Hoon Rim, Taekyun Kim, Sung-Soo Pyo
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

On the Harmonic and Hyperharmonic Fibonacci Numbers

open access: yes, 2015
In this paper, we study the theory of the harmonic and the hyperharmonic Fibonacci numbers. Also, we get some combinatoric identities like as harmonic and hyperharmonic numbers and we obtain some useful formulas for $\mathbb{F}_{n}$, which is finite sums
Kesim, Seyhun   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Some extensions of Chu's formulas and further combinatorial identities [PDF]

open access: yesMathematica Bohemica
We present some extensions of Chu's formulas and several striking generalizations of some well-known combinatorial identities. As applications, some new identities on binomial sums, harmonic numbers, and the generalized harmonic numbers are also derived.
Said Zriaa, Mohammed Mouçouf
doaj   +1 more source

Parametric Euler Sums of Harmonic Numbers

open access: yes, 2022
We define a parametric variant of generalized Euler sums and construct contour integration to give some explicit evaluations of these parametric Euler sums. In particular, we establish several explicit formulas of (Hurwitz) zeta functions, linear and quadratic parametric Euler sums. Furthermore, we also give an explicit evaluation of alternating double
Quan, Junjie   +3 more
openaire   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Some Congruences for Sums Involving Harmonic Numbers

open access: yesCumhuriyet Science Journal, 2018
In this paper, we establish some congruences involving sums withharmonic numbers and the terms of second-order linear sequences.
Neşe Ömür, Sibel Koparal
doaj   +1 more source

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