Results 71 to 80 of about 351,945 (274)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Hypergeometric series and harmonic number identities

open access: yesAdvances in Applied Mathematics, 2005
10 ...
CHU, Wenchang, DEDONNO L.
openaire   +4 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Certain Mathematical Constants Associated with Harmonic Numbers and Higher-Dimensional Harmonic Sums

open access: yesMathematics
The Euler–Mascheroni constant γ, defined as the limiting difference between the harmonic numbers Hn and logn, has long been studied and appears in diverse areas of number theory, analysis, and special functions.
Junesang Choi
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Some Sums Involving Generalized Harmonic and r-Derangement Numbers

open access: yesCumhuriyet Science Journal
In this paper, we derive some sums involving generalized harmonic and r-derangement numbers by using generating functions of these numbers and some combinatorial identities. The relationship between Daehee numbers and generalized harmonic numbers of rank
Sibel Koparal
doaj   +1 more source

Harmonic Numbers and Cubed Binomial Coefficients [PDF]

open access: yesInternational Journal of Combinatorics, 2011
Euler related results on the sum of the ratio of harmonic numbers and cubed binomial coefficients are investigated in this paper. Integral and closed-form representation of sums are developed in terms of zeta and polygamma functions. The given representations are new.
openaire   +3 more sources

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

Formulae concerning multiple harmonic-like numbers [PDF]

open access: yesContributions to Mathematics, 2023
Yulei Chen, Dongwei Guo
doaj   +1 more source

Some identities associated with degenerate harmonic and hyperharmonic numbers

open access: yesMathematical and Computer Modelling of Dynamical Systems
The study of degenerate versions of special polynomials and numbers has seen significant progress in recent years. In this paper, we establish several identities involving degenerate harmonic and hyperharmonic numbers, which are degenerate versions of ...
Qixiang Wang   +4 more
doaj   +1 more source

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