Results 61 to 70 of about 288,836 (289)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

The Reduced Basis Method for Time‐Harmonic Maxwell's Equations [PDF]

open access: yesPAMM, 2012
AbstractThe Reduced Basis Method (RBM) generates low‐order models of parametrized PDEs to allow for efficient evaluation of the input‐output behaviour in many‐query and real‐time contexts. The RBM approach is decomposed into a time‐consuming offline‐phase, which generates a surrogate model and an online phase, which performs fast parameter evaluations.
Benner, P. ; https://orcid.org/0000-0003-3362-4103   +1 more
openaire   +2 more sources

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Spatiotemporal phase-matching in capillary high-harmonic generation [PDF]

open access: yes, 2012
We present a simple phase-matching model that takes into account the full spatiotemporal nature of capillary high-harmonic generation. Spectra predicted from the model are compared to experimental results for a number of gases and are shown to reproduce ...
Rogers, Edward T.F.   +22 more
core   +1 more source

Simulation of meshing characteristics of harmonic reducer and experimental verification

open access: yesAdvances in Mechanical Engineering, 2018
This article studies the causes of the time-varying stiffness of harmonic drive gear and the number of meshing teeth and the meshing length under different torques. Multi-pair tooth meshing characterizes the operating process of the harmonic gear reducer.
Jianfeng Ma   +3 more
doaj   +1 more source

Reduced Harmonic Representation of Partitions

open access: yes, 2011
In the present article the reduced integral representation of partitions in terms of harmonic products has been derived first by using hypergeometry and the new concept of fractional sum and secondly by studying the Fourier series of the kernel function appearing in the integral representation.
openaire   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

固体润滑谐波减速器真空运行性能的试验

open access: yesJixie chuandong, 1998
Harmonic gear drives are widely used in space mechanism in nearly decades, but the solid lubrications of the reducer is a difficult problem until now. In this paper, the authors studied vacuum running behaviors of XB 3 60 harmonic reducer under solid ...
孙晓军   +5 more
doaj  

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

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