Results 71 to 80 of about 173,277 (307)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Effect of Bulk Capacitor on Harmonics of Energy-Efficient Devices

open access: yesIEEE Access
This paper develops analytical expressions to describe the behavior of harmonic components in rectifier circuits. It examines how harmonic content in the supply voltage influences the harmonic currents drawn by energy-efficient loads.
Kamran Daniel   +6 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Comparison of different optimization criteria for optimal sizing of hybrid active power filters parameters [PDF]

open access: yes, 2014
Praise Worthy Prize granted a permission for Brunel University London to archive this article in BURA.Harmonic distortion in power systems has increased considerably due to the increasing use of nonlinear loads in industrial firms and elsewhere.
Elmathana, KTM, Zobaa, AF
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Harmonic Distortion Study of a Photovoltaic Generator in a Microgrid under Disturbances

open access: yesEnergies
This paper describes research on the harmonic-distortion capacity of a single-stage photovoltaic (PV) 3.68 kWp generator in a microgrid configuration.
Nestor F. Guerrero-Rodríguez   +5 more
doaj   +1 more source

Inductive measurements of third-harmonic voltage and critical current density in bulk superconductors

open access: yes, 2003
We propose an inductive method to measure critical current density $J_c$ in bulk superconductors. In this method, an ac magnetic field is generated by a drive current $I_0$ flowing in a small coil mounted just above the flat surface of superconductors ...
Mawatari, Yasunori   +2 more
core   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

Modeling and Control of Grid-Forming Active Power Filters for Harmonic Suppression and Enhanced Power Quality

open access: yesApplied Sciences
Grid-forming converters (GFMCs) have gained significant attention for their functionality in grid voltage formation and grid-supportive services. However, managing harmonic distortions caused by nonlinear loads remains a critical challenge in weak grids.
Muhammad Waqas Qaisar   +2 more
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

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