Results 51 to 60 of about 334,498 (301)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Deterministic and Stochastic Study of Wind Farm Harmonic Currents [PDF]

open access: yesIEEE Transactions on Energy Conversion, 2010
Wind farm harmonic emissions are a well-known power quality problem, but little data based on actual wind farm measurements are available in literature. In this paper, harmonic emissions of an 18MWwind farm are investigated using extensive measurements, and the deterministic and stochastic characterization of wind farm harmonic currents is analyzed ...
Sainz Sapera, Luis   +3 more
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Synchronous reluctance machines with new type of fractional‐slot concentrated‐windings based on the concept of stator slot shifting

open access: yesIET Electric Power Applications, 2023
Fractional‐slot concentrated‐windings are appreciated for their simple construction, short end‐winding length, high copper fill factor, low cogging torque, good field‐weakening capability and fault‐tolerant ability.
Seyed Mahdiar Taghavi Araghi   +2 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

Analysis of DC Winding Induced Voltage in Wound-Rotor Synchronous Machines by Using the Air-Gap Field Modulation Principle

open access: yesWorld Electric Vehicle Journal, 2022
In order to analyze the DC winding induced voltage in the wound-rotor synchronous machine, this paper uses the air-gap field modulation principle to investigate its operation mechanism and harmonic order.
Wentao Zhang   +5 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Control Strategies for Open-End Winding Drives Operating in the Flux-Weakening Region [PDF]

open access: yes, 2013
This paper presents and compares control strategies for three-phase open-end winding drives operating in the flux-weakening region. A six-leg inverter with a single dc-link is associated with the machine in order to use a single energy source.
KESTELYN, Xavier   +4 more
core   +1 more source

Parameter Calculation and Working Characteristic Analysis of a New Type of Magnetic Integrated CRT

open access: yesIEEE Access, 2022
The working characteristic of an electromagnetic equipment is an important reference standard for measuring its working performance. In this paper, we take a new type of magnetic integrated controllable reactor of transformer type (CRT) as the research ...
Wang Tiange   +3 more
doaj   +1 more source

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