Results 151 to 160 of about 58,150 (291)

Global pharmacovigilance reporting: comparative analysis of adverse event obligations across five major regulatory authorities. [PDF]

Front Drug Saf Regul
Bernaus CG, Bournissen ML.
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Efficient Direct Recycling of Spent Batteries: Integrated Lithiation and Delamination

Advanced Science, EarlyView.
An integrated process for the delamination and relithiation of spent cathodes, LixNi0.6Co0.2Mn0.2O2 and LixFePO4, under open‐air conditions is proposed. The transition‐metal (Ni) oxidation state in the cathode is reduced by the oxidation of diethylene glycol, facilitating relithiation. Glycol aldehyde formation induces 100% electrode delamination.
Jeonghwan Song, Seok Hyun Song, Dokyeong Han, Jaehyun Noh, Jayoung Kim, Min Jeong Kim, Hayong Song, Jeong‐Sun Park, Jaekook Kim, Jiyoung Ma, Jinju Song, Jung‐Je Woo   +11 more
wiley   +1 more source

Substandard and Falsified Medicines, Regulatory Capacity and Public Health: A Narrative Review With a Focus on Africa. [PDF]

Public Health Chall
Vandy A, Samai NO, Abiri OT, Lahai M, Thomas F, Buffa T, Mansaray S, Turay A, Osborne A.   +8 more
europepmc   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Building the foundations for global data banking in digital phenotyping for mental health. [PDF]

NPP Digit Psychiatry Neurosci
O'Dea B, Naz S, McLoughlin LT, Whitton AE.   +3 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

A temporally harmonised gridded building-stock dataset for the Global South, 2016-2023. [PDF]

Gates Open Res
Zhang WB, McKeen T, Priyatikanto R, Fang W, Tejedor-Garavito N, Sorichetta A, Tatem AJ, Bondarenko M.   +7 more
europepmc   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Development and evaluation of wrist- and thigh-worn accelerometer algorithms using self-training machine learning models for classification of activity type and posture: towards device placement-agnostic methods in the ProPASS consortium. [PDF]

Int J Behav Nutr Phys Act
Ahmadi MN, Koemel N, Biswas R, Holtermann A, Koster A, Atkins A, Pulsford R, Del Pozo Cruz B, Rangul V, Mitchell J, Blodgett J, Hettiarachchi P, Svartengren M, Granat M, Clark B, Hamer M, Stamatakis E.   +16 more
europepmc   +1 more source