Results 51 to 60 of about 308,323 (313)

Harmonic and relative harmonic dimensions

open access: yesAnnales Academiae Scientiarum Fennicae. Series A. I. Mathematica, 1985
On an open Riemann surface R of Heins type (i.e. R is parabolic with a single ideal boundary component, \(\delta\) R), this paper considers the relationship between the harmonic dimension of the ideal boundary, dim \(\delta\) R, and the relative harmonic dimension of the ideal boundary, \(\dim_ F\delta R\).
Nakai, Mitsuru, Sario, Leo
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Scanner Invariant Representations for Diffusion MRI Harmonization [PDF]

open access: yes, 2020
Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject to variation
Abdi H   +8 more
core   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Quantitative MRI Harmonization to Maximize Clinical Impact: The RIN–Neuroimaging Network

open access: yesFrontiers in Neurology, 2022
Neuroimaging studies often lack reproducibility, one of the cardinal features of the scientific method. Multisite collaboration initiatives increase sample size and limit methodological flexibility, therefore providing the foundation for increased ...
Anna Nigri   +49 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Ethnosociological Studies in the Republic of Mordovia in 1990–2010: A Retrospective Analysis

open access: yesРегионология, 2019
Introduction. Ethnosociological monitoring in a polyethnic region is conducted not only due to the need for an assessment of the public policy regulation in this field, but also due to the increase in the heuristic potential for preventing various kinds ...
Vladimir V. Kozin, Sergey G. Ushkin
doaj   +1 more source

Harmonization of Brain Diffusion MRI: Concepts and Methods

open access: yesFrontiers in Neuroscience, 2020
MRI diffusion data suffers from significant inter- and intra-site variability, which hinders multi-site and/or longitudinal diffusion studies. This variability may arise from a range of factors, such as hardware, reconstruction algorithms and acquisition
Maíra Siqueira Pinto   +10 more
doaj   +1 more source

Control of multiscale systems with constraints. 1. Basic principles of the concept of evolution of systems with varying constraints [PDF]

open access: yes, 2012
Physical fundamentals of the self-organizing theory for the system with varying constraints are considered. A variation principle, specifically the principle of dynamic harmonization as a generalization of the Gauss-Hertz principle for the systems with ...
Adamenko, S., Bolotov, V., Novikov, V.
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

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