Results 91 to 100 of about 178,596 (313)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

The educational potential of the Harmony Project [PDF]

open access: yes, 2019
This research, funded by Canterbury Christ Church University, involved semi-structured interviews with senior leaders from ten schools in England who are engaging with principles of Harmony. Interviews were conducted between May and July 2019 by research
J. Marshall., Kemp, N., Pagden, A.
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi   +17 more
wiley   +1 more source

“Modulate! modulate! modulate! but do not change the key.” The development and transformation of the term modulation in the 19th-century French theory

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2018
Historical sources recount an anecdote about a class on organ improvisation taught by the already renowned composer and organist César Franck (1822 – 1890) and attended by young Claude Debussy (1862 – 1918) in the 1880s.
Nikola Komatović
doaj   +1 more source

Harmony Baptist Association

open access: yes, 1918
Harmony Baptist Association held its first annual session in 1918 at Star City. Member churches included Dumas; Hickory Grove; and Star City; as well as Beech Street, First Baptist, Hazel Street, and Ohio Street, all of Pine Bluff.
Harmony Baptist Association,
core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Democracy and Climate Change: a Confucian Proposal

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2018
Democracy is one of the West’s most important contributions to universal human heritage. Still it presents some drawbacks in the ways it relates to certain global problems, especially climate change.
Aurelio De Prada
doaj   +1 more source

Harmony Phase 0/A

open access: yes, 2019
This technical note provides some general considerations on the geophysical requirements of the Harmony L2 Ocean products and their implications to the mission requirements.
Johnsen, Harald
core  

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

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