Results 71 to 80 of about 873,634 (289)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Lutheran Confessions: A Harmony and Resource Book [PDF]

open access: yes, 1980
Tjernagel, November S. Lutheran Confessions: A Harmony and Resource Book.
Nostbakken, Roger W.
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Harmony

open access: yes, 2020
Harmony is a special feeling you get when you notice two ore more things fitting together really well. Different experiences evoke harmony for different people. In this yoga-based meditation, you invite a memory of a time when you experienced a strong sense of harmony. Connect with the harmony. Explore what it feels like in your body and mind.
openaire   +2 more sources

Group singing as a resource for the development of a healthy public: a study of adult group singing

open access: yesHumanities & Social Sciences Communications, 2020
A growing body of evidence points to a wide range of benefits arising from participation in group singing. Group singing requires participants to engage with each other in a simultaneous musical dialogue in a pluralistic and emergent context, creating a ...
David A. Camlin   +2 more
doaj   +1 more source

A context based planning approach for comparative analysis of centralised and decentralised wastewater systems sustainability [PDF]

open access: yes, 2012
Wastewater management is traditionally viewed primarily as a technical and economic issue. However, it is now recognised that these are some of the criteria in an array of other factors that affect sustainability.
Musiyarira, Harmony Kuitakwashe
core  

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

A phase 1 study of a second experience with Group Retreat Psilocybin Therapy for partial responders after a first experience

open access: yesFrontiers in Public Health
IntroductionPsilocybin therapy has demonstrated efficacy for cancer-related anxiety and depression, but resource-intensive individual treatment models raise important questions for psychedelic public health about equitable access and scalability.
Anthony L. Back   +17 more
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

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