Results 41 to 50 of about 2,858,166 (247)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Applied Sciences, 2020 The Harmony Search algorithm has attracted a lot of interest in the past years because of its simplicity and efficiency. This led many scientists to develop various variants for many applications.
Fares M’zoughi +3 more
doaj +1 more source
A Hybrid Harmony Search Algorithm for Solving Dynamic Optimisation Problems [PDF]
, 2014 Many optimisation problems are dynamic in the sense that changes occur during the optimisation process, and therefore are more challenging than the stationary problems.
Turky, Ayad +4 more
core +2 more sources
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Economic Dispatch Using Parameter-Setting-Free Harmony Search
Journal of Applied Mathematics, 2013 Economic dispatch is one of the popular energy system optimization problems. Recently, it has been solved by various phenomenon-mimicking metaheuristic algorithms such as genetic algorithm, tabu search, evolutionary programming, particle swarm ...
Zong Woo Geem
doaj +1 more source
A Hybrid Cultural Harmony Search Algorithm for Constrained Optimization Problem of Diesel Blending
IEEE Access, 2020 This paper studies the constrained optimization problem for nonlinear diesel blending. A new hybrid algorithm called cultural harmony search algorithm is presented to solve the proposed optimization problem, which uses cultural knowledge in the belief ...
Min Gao +3 more
doaj +1 more source
Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran +13 more
wiley +1 more source
Optimum Design of Steel Frames via Harmony Search Algorithm
, 2009 A harmony search algorithm is presented for optimum design of planar and space steel frames in this chapter. Harmony search (HS) is a meta-heuristic search method.
Degertekin, S. O.
core +1 more source
An improved harmony search algorithm for structural optimization
, 2016 碩士調和搜尋演算法是一種模仿樂團演奏練習將曲目調整至最協調的現象應用到最佳化系統之方法。調和搜尋演算法參數設定簡單並以隨機方式進行搜尋，可以作大範圍之全域搜尋。本研究是應用改良式調和搜尋演算法於結構最佳化設計之研究。改良式調和搜尋演算法採用了新的改良機制，藉由線性變化的調和記憶考慮機率及調音機率改善搜尋範圍的控制能力，並改良微調步距隨搜尋過程作變化增加區域搜尋能力，以提升準確性並優化搜尋能力。 本研究將ANSYS有限元素分析軟體中的APDL語法與FORTRAN程式結合成一系統程式 ...
劉宇哲;Liou, Yu-Jhe
core +2 more sources