Results 101 to 110 of about 4,950,885 (240)

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

A Hybrid Heuristic Harmony Search Algorithm for the Vehicle Routing Problem With Time Windows

IEEE Access
In this paper, we present a hybrid heuristic method based on the harmonic search algorithm to solve the vehicle routing problem with time windows. The importance of efficient path planning in logistics and supply chain management is emphasized herein ...
Yang Zhang, Jiacheng Li
doaj   +1 more source

Space‐Time Metasurface Antenna Enabled High‐Dimensional Electromagnetic Modulation for Intrinsic Physical Layer Security

Advanced Science, EarlyView.
The concept of high‐dimensional EM modulation using the STMA for physical layer secure communication is illustrated in figure. The STMA consists of a series of programmable unit cells, with 1‐bit reconfigurable phase states (0/π). The STMA is excited by a monochromatic continuous wave (CW) at frequency fc and controlled by a field‐programmable gate ...
Xinyu Fang, Yiqing Sun, Chenfeng Yang, Siran Wang, Zheng Xing Wang, Kaixu Wang, Geng‐Bo Wu   +6 more
wiley   +1 more source

Partial Transmit Sequence Optimization Using Improved Harmony Search Algorithm for PAPR Reduction in OFDM

ETRI Journal, 2017
This paper considers the use of the Partial Transmit Sequence (PTS) technique to reduce the Peak‐to‐Average Power Ratio (PAPR) of an Orthogonal Frequency Division Multiplexing signal in wireless communication systems.
Mangal Singh, Sarat Kumar Patra
doaj   +1 more source

Improved Harmony Search Algorithm in Application of Vulcanization Workshop Scheduling

, 2020
: For solving the problem of low productivity and low machine utilization caused by unreasonable assignment in tire vulcanizing process, an improved Discrete Harmony Search (Improved Harmony Search, IHS) Algorithm was proposed to optimize the maximum ...
Yan, Wang, Ji, Zhicheng, Wu, Longcheng, Song, Huang   +3 more
core   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Missing data imputation with Harmony Search Algorithm

International Journal of Combinatorial Optimization Problems and Informatics
Incomplete data poses a significant obstacle in data science and machine learning, influencing model outcomes and occurring commonly across domains such as health, nutrition, electricity, agriculture, chemistry and water resources. Missing data refers to the absence of information for one or more variables in a dataset. Accurate imputation is therefore
Edgar Alberto Oviedo Salas, Fausto Antonio Balderas-Jaramillo   +1 more
openaire   +2 more sources

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Harmony search algorithm for location-routing problem in supply chain network design

, 2019
The interdependence of facility location and vehicle routing has been recognized among the practitioners and researchers. The integration of these problems is more challenging in a supply chain network design problem.
Misni, F., Lee, L. S.
core   +1 more source

An application for solving minimization problems using the Harmony search algorithm

SoftwareX
The Harmony Search (HS) algorithm, inspired by the improvisational process of musicians, offers a novel and effective approach to optimization problems. This paper presents an application designed to solve a wide range of minimization problems using the ...
Fazliddin Makhmudov, Dusmurod Kilichev, Young Im Cho   +2 more
doaj   +1 more source