Results 101 to 110 of about 45,729 (287)

Harmony Search Algorithm for Patient Admission Scheduling Problem

open access: yesJournal of Intelligent Systems, 2018
The patient admission scheduling (PAS) problem is an optimization problem in which we assign patients automatically to beds for a specific period of time while preserving their medical requirements and their preferences. In this paper, we present a novel
Abu Doush Iyad   +6 more
doaj   +1 more source

A Global Optimisation Toolbox for Massively Parallel Engineering Optimisation [PDF]

open access: yes, 2010
A software platform for global optimisation, called PaGMO, has been developed within the Advanced Concepts Team (ACT) at the European Space Agency, and was recently released as an open-source project.
Biscani, Francesco   +2 more
core  

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao   +12 more
wiley   +1 more source

A Hybrid Heuristic Harmony Search Algorithm for the Vehicle Routing Problem With Time Windows

open access: yesIEEE Access
In this paper, we present a hybrid heuristic method based on the harmonic search algorithm to solve the vehicle routing problem with time windows. The importance of efficient path planning in logistics and supply chain management is emphasized herein ...
Yang Zhang, Jiacheng Li
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Partial Transmit Sequence Optimization Using Improved Harmony Search Algorithm for PAPR Reduction in OFDM

open access: yesETRI Journal, 2017
This paper considers the use of the Partial Transmit Sequence (PTS) technique to reduce the Peak‐to‐Average Power Ratio (PAPR) of an Orthogonal Frequency Division Multiplexing signal in wireless communication systems.
Mangal Singh, Sarat Kumar Patra
doaj   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

open access: yesAdvanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang   +12 more
wiley   +1 more source

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