Results 111 to 120 of about 7,467 (294)

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

open access: yesAdvanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Nurse Scheduling with Opposition-Based Parallel Harmony Search Algorithm

open access: yesJournal of Intelligent Systems, 2019
One of the advances made in the management of human resources for the effective implementation of service delivery is the creation of personnel schedules.
Cetin Yagmur Ece, Sarucan Ahmet
doaj   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

Radiation‐Induced Tumor‐Intrinsic LTβR N‐Glycosylation Suppresses Pyroptosis Through TRIM28‐Mediated PCBP2 SUMOylation to Promote Gastric Cancer Radioresistance

open access: yesAdvanced Science, EarlyView.
Radiotherapy triggers LTβR N‐glycosylation, enhancing its overall protein stability and nuclear retention. This accumulation drives TRIM28‐mediated PCBP2 SUMOylation, suppressing pyroptosis and conferring gastric cancer radioresistance. Therapeutically, a targeted nanoplatform (cRGD‐Lipo@EMD) effectively disrupts this regulatory axis, offering a highly
Weijie Zang   +8 more
wiley   +1 more source

Optimal reactive power dispatch considering multi-type FACTS devices using harmony search algorithms

open access: yesAutomatika, 2018
Optimal Reactive Power Dispatch (ORPD) plays an important role for the secure and reliable operation of power systems. The main purpose of ORPD is to find the settings of control variables such as voltage rating of generators, reactive power injection of
D. Karthikaikannan, G. Ravi
doaj   +1 more source

An exciting Approach to Theoretical Spectroscopy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno   +29 more
wiley   +1 more source

Harmony search algorithm for location-routing problem in supply chain network design

open access: yes, 2019
The interdependence of facility location and vehicle routing has been recognized among the practitioners and researchers. The integration of these problems is more challenging in a supply chain network design problem.
Misni, F., Lee, L. S.
core  

A local-best harmony search algorithm with dynamic subpopulations

open access: yes, 2010
This article presents a local-best harmony search algorithm with dynamic subpopulations (DLHS) for solving the bound-constrained continuous optimization problems.
Tasgetiren, M.F.   +3 more
core   +1 more source

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