Results 31 to 40 of about 569,121 (307)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A High Performance Remote Sensing Product Generation System Based on a Service Oriented Architecture for the Next Generation of Geostationary Operational Environmental Satellites

open access: yesRemote Sensing, 2015
The Geostationary Operational Environmental Satellite (GOES) series R, S, T, U (GOES-R) will collect remote sensing data at several orders of magnitude compared to legacy missions, 24 × 7, over its 20-year operational lifecycle.
Satya Kalluri   +6 more
doaj   +1 more source

Harris seeds / Joseph Harris Co. [PDF]

open access: yes, 1897
Company established by Joseph Harris in 1879 at Moreton Farm, NY. ; With no Harris family members to continue with the business, Joe Harris sold the company to a large corporation in 1979.

core  

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

Harris seeds / Joseph Harris Co. [PDF]

open access: yes, 1884
Company established by Joseph Harris in 1879 at Moreton Farm, NY. ; With no Harris family members to continue with the business, Joe Harris sold the company to a large corporation in 1979.

core  

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Electrochromic Adaptive Solar Heater and Sub‐Ambient Passive Daytime Radiative Cooler

open access: yesAdvanced Materials, EarlyView.
An electrochromic Cu–Bi nanocluster device dynamically switches between solar heating and daytime sub‐ambient radiative cooling without mechanical motion. Defect‐activated graphene, minimized electrolyte loss, and pulse‐assisted reversible electrodeposition enable opposite solar and mid‐infrared modulation in one opaque platform, establishing a design ...
Chenxi Sui   +11 more
wiley   +1 more source

Data‐Driven Bulldozer Blade Control for Autonomous Terrain Leveling

open access: yesAdvanced Robotics Research, EarlyView.
A simulation‐driven framework for autonomous bulldozer leveling is presented, combining high‐fidelity terramechanics simulation with a neural‐network‐based reduced‐order model. Gradient‐based optimization enables efficient, low‐level blade control that balances leveling quality and operation time.
Harry Zhang   +5 more
wiley   +1 more source

Implementation strategy and cost of Mozambique’s HPV vaccine demonstration project

open access: yesBMC Public Health, 2019
Background Cost is an important determinant of health program implementation. In this study, we conducted a comprehensive evaluation of the implementation strategy of Mozambique’s school-based HPV vaccine demonstration project.
Caroline Soi   +7 more
doaj   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

open access: yesAdvanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu   +7 more
wiley   +1 more source

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