Results 101 to 110 of about 597,613 (297)

Effect of a luteal phase rescue protocol on live birth rates in frozen embryo transfer cycles

open access: yesFrontiers in Reproductive Health
IntroductionFrozen embryo transfer (FET) is a standard procedure that improves live birth rates and reduces ovarian hyperstimulation risks. Optimizing luteal phase support with hormone replacement therapy (HRT), particularly by progesterone ...
Chadi Yazbeck   +7 more
doaj   +1 more source

MHD Mixed Convection and Entropy Generation in a Lid-Driven Triangular Cavity for Various Electrical Conductivity Models

open access: yesEntropy, 2018
In this study, effects of different electrical conductivity models for magneto- hydrodynamic mixed convection of nanofluids in a lid-driven triangular cavity was numerically investigated with a finite element method.
Ali J. Chamkha   +2 more
doaj   +1 more source

Bridging the Gap: Student Voices on Recruitment and Retention in Ecology

open access: yesThe Bulletin of the Ecological Society of America, EarlyView.
Abstract Students entering ecology and environmental science face a variety of challenges, including limited awareness of career paths, lack of mentorship, and difficulties connecting with peers and faculty. These challenges are often amplified for students from marginalized backgrounds, who may also encounter microaggressions, underrepresentation, and
Alexis Ellis   +9 more
wiley   +1 more source

Influence of Zn2+ and Oxygen Supply on Malic Acid Production and Growth of Aspergillus oryzae

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Malic acid is a valuable platform chemical traditionally derived from fossil‐based resources. Microbial cultivation with Aspergillus oryzae offers a sustainable alternative based on renewable feedstocks. In this study, a well‐established minimal medium for malic acid production, commonly used in previous research to ensure reproducibility, was
Lukas Hartmann   +3 more
wiley   +1 more source

Gaussian Processes for Predictive QSAR Modeling of Chromatographic Processes

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Chromatography is a key unit operation in the biopharmaceutical manufacturing process used for protein purification and polishing. Design and optimization of these processes are resource‐intensive resulting from the complex combinatorial design space.
Harini Narayanan   +7 more
wiley   +1 more source

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan   +4 more
wiley   +1 more source

Advancing Malic Acid Production of Aspergillus oryzae: Combined Process Optimization and Application of Various Substrates

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT In light of climate change and growing resource scarcity, microbial production of organic acids offers a sustainable alternative to fossil‐based chemical synthesis. In this study, malic acid production by Aspergillus oryzae was optimized through cultivation temperature adjustment and biotin supplementation, while organic acid formation from ...
Lukas Hartmann   +6 more
wiley   +1 more source

Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum

open access: yesBiotechnology and Bioengineering, EarlyView.
Conventional bulk media are often unsuitable for single‐cell cultivation and analysis because they provide excess nutrients or lack essential components. Redesigning the medium allows for controlled, defined growth, enabling the development of a robust minimal medium that supports quantitative and reproducible single‐cell analysis across different ...
Judith Wegmann   +5 more
wiley   +1 more source

Engineering Murine Cross‐Reactivity Into an Affibody to Human Death Receptor 5

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Interspecies cross‐reactive protein therapeutics that target conserved epitopes across species are critical for translational research. The present study showcases the engineering of an affibody molecule, originally discovered for binding to human death receptor 5 (hDR5) with 94 nM affinity, to simultaneously acquire cross‐reactivity to murine
Tse‐Han Kuo   +3 more
wiley   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

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