Results 101 to 110 of about 460,055 (310)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Oregon Harvest for Schools - wheat
, 2021 Promoting Oregon wheat in school settings and to families.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Julius-Kühn-Archiv, 2018 ECO2FUME® phosphine fumigant was used to fumigate milled rice in a commercial plastic bag (5 kg) and milled rice in a jumbo bag (1,000 kg) under gas-proof sheets to assess its performance against a mixed-age culture of Sitophilus zeamais, Tribolium ...
Kengkanpanich, Rungsima +2 more
doaj +1 more source
Oregon Harvest for Schools - parsnips
, 2021 Promoting Oregon parsnips in school settings and to families.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oregon Harvest for Schools - leeks (English)
, 2021 Promoting Oregon leeks in school settings and to families.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Food, Nutrition and HealthCinnamon essential oil (CEO) is gaining attention as a natural food preservative due to growing consumer demand for safe, high-quality, and clean-label products.
Shabahat Ali +4 more
doaj +1 more source
Oregon Harvest for Schools - string beans
, 2021 Promoting Oregon string beans in school settings and to families.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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