Results 111 to 120 of about 1,219,741 (305)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Characterization of Zalaria obscura Y1223 hydrolases: implications for lignocellulose conversion

open access: yesAMB Express
Overconsumption of fossil fuel reserves and its adverse effects has sparked interest in the production of second-generation biofuels due to the abundance of lignocellulosic waste and potential energy crops.
Jeremy J. Boonzaier   +4 more
doaj   +1 more source

Forecasting Crop Basis Using Historical Averages Supplemented with Current Market Information [PDF]

open access: yes
This research compares practical methods of forecasting basis, using current market information for wheat, soybeans, corn, and milo (grain sorghum) in Kansas.
Dhuyvetter, Kevin C.   +2 more
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Exploring Functional Properties of Mantis Shrimp (Miyakella nepa) Protein Powder for Sustainable Food Applications

open access: yesInternational Journal of Bio-Resource and Stress Management
The experiment was conducted from January to August, 2023 at the Central Institute of Fisheries Education, Mumbai, India, to investigate the potential of mantis shrimp (Miyakella nepa) as a resource for developing value-added food products.
D. Varsha   +6 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Total flavonoids from Abelmoschus manihot (L.) improve diabetes nephropathy by regulating the gut–kidney axis

open access: yesFrontiers in Medicine
BackgroundA recent clinical study demonstrated that Huangkui capsule (with its bioactive constituents being total flavones extracted from Abelmoschus manihot (L.), TFA) combined with irbesartan provides effective therapy for type 2 diabetes (T2D ...
Hongmei Yu   +5 more
doaj   +1 more source

Bromegrass in Alaska. VI. Effects of a Broad Array of Harvest Schedules and Frequencies on Forage Yield and Quality and on Subsequent Winter Survival of Cultivars Manchar and Polar [PDF]

open access: yes, 1997
Objectives of this study were to compare several schedules and frequencies of forage harvest of smooth bromegrass (Bromus inermis Leyss.): (a) for distribution of forage yields and total productivity in the year of differential harvests, (b) for ...
Klebesadel, Leslie J.
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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