Results 151 to 160 of about 1,936,197 (337)

Green solvent extraction of health boosting phenolics from pigeon pea husk

open access: yesScientific Reports
The optimization of phenolic compound extraction from pigeon pea (Cajanus cajan L.) husk was explored by manipulating three key process variables: aqueous ethanol concentration (20–60% v/v), extraction temperature (30–60 °C), and extraction time (2–6 h).
Deepika Goswami   +4 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

The incidence of post-harvest problems among small farmers surveyed in three regions of the Limpopo Province [PDF]

open access: yes
High yielding varieties and new production technology have vastly increased the world's agricultural production and provided rural incomes and affordable food for large parts of the population.
Randela, Rendani
core   +1 more source

Integration of Elymus repens control and post-harvest catch crop growing in organic cropping systems [PDF]

open access: yes, 2005
In Northern Europe, Elymus repens (L.) Gould infestations are traditionally controlled by repeated stubble cultivation in the period from harvest to ploughing in autumn. However, in organic farming, post-harvest tillage is undesirable due to the need for
Bertelsen, Inger   +2 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Social-ecological soundscapes: examining aircraft-harvester-caribou conflict in Arctic Alaska [PDF]

open access: yes, 2017
Thesis (M.S.) University of Alaska Fairbanks, 2017As human development expands across the Arctic, it is crucial to carefully assess the impacts to remote natural ecosystems and to indigenous communities that rely on wild resources for nutritional and ...
Stinchcomb, Taylor R.
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Optimization, quality and shelf-life analysis of jam production from blended cactus pear (Opuntia Ficus-Indica) and strawberry (Fragaria) fruits

open access: yesDiscover Food
The cactus pear (Opuntia ficus-indica) is a resilient, nutritious fruit suitable for sustainable food development in semi-arid regions, but faces postharvest challenges like short shelf-life.
Mizan Leul   +6 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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