Results 141 to 150 of about 3,945,564 (229)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Deciphering the genetic basis of novel traits that discriminate useful and non-useful biomass to enhance harvest index in wheat. [PDF]

Plant Genome
Shahi D, Guo J, Babar MA, Pradhan S, Avci M, Khan N, McBreen J, Rayamajhi S, Liu Z, Bai G, Amand PS, Bernardo A, Reynolds M, Molero G, Sukumaran S, Foulkes J, Khan J.   +16 more
europepmc   +1 more source

A Novel Stay-Green Mutant of Rice with Delayed Leaf Senescence and Better Harvest Index Confers Drought Tolerance. [PDF]

Plants (Basel), 2019
Ramkumar MK, Senthil Kumar S, Gaikwad K, Pandey R, Chinnusamy V, Singh NK, Singh AK, Mohapatra T, Sevanthi AM.   +8 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

HI from the Sky: Estimating harvest index from UAVs combined with machine learning. [PDF]

Plant Physiol
Burgess AJ.
europepmc   +1 more source

Understanding the Genetic Basis of Spike Fertility to Improve Grain Number, Harvest Index, and Grain Yield in Wheat Under High Temperature Stress Environments. [PDF]

Front Plant Sci, 2019
Pradhan S, Babar MA, Robbins K, Bai G, Mason RE, Khan J, Shahi D, Avci M, Guo J, Maksud Hossain M, Bhatta M, Mergoum M, Asseng S, Amand PS, Gezan S, Baik BK, Blount A, Bernardo A.   +17 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Correction to: Strategic crossing of biomass and harvest index-source and sink-achieves genetic gains in wheat. [PDF]

Euphytica, 2018
Reynolds MP, Pask AJD, Hoppitt WJE, Sonder K, Sukumaran S, Molero G, Pierre CS, Payne T, Singh RP, Braun HJ, Gonzalez FG, Terrile II, Barma NCD, Hakim A, He Z, Fan Z, Novoselovic D, Maghraby M, Gad KIM, Galal EG, Hagras A, Mohamed MM, Morad AFA, Kumar U, Singh GP, Naik R, Kalappanavar IK, Biradar S, Sai Prasad SV, Chatrath R, Sharma I, Panchabhai K, Sohu VS, Mavi GS, Mishra VK, Balasubramaniam A, Jalal-Kamali MR, Khodarahmi M, Dastfal M, Tabib-Ghaffari SM, Jafarby J, Nikzad AR, Moghaddam HA, Ghojogh H, Mehraban A, Solís-Moya E, Camacho-Casas MA, Figueroa-López P, Ireta-Moreno J, Alvarado-Padilla JI, Borbón-Gracia A, Torres A, Quiche YN, Upadhyay SR, Pandey D, Imtiaz M, Rehman MU, Hussain M, Hussain M, Ud-Din R, Qamar M, Sohail M, Mujahid MY, Ahmad G, Khan AJ, Sial MA, Mustatea P, von Well E, Ncala M, de Groot S, Hussein AHA, Tahir ISA, Idris AAM, Elamein HMM, Manes Y, Joshi AK.   +75 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Faba bean and pea harvest index estimations using aerial-based multimodal data and machine learning algorithms. [PDF]

Plant Physiol
Ji Y, Liu Z, Cui Y, Liu R, Chen Z, Zong X, Yang T.   +6 more
europepmc   +1 more source