Results 131 to 140 of about 1,168,516 (371)

Byproduct yields of serially harvested calf-fed Holstein steers fed zilpaterol hydrochloride1 [PDF]

open access: bronze, 2016
N. D. May   +5 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Bank erosion of the Tŕstie stream: BANCS model predictions vs. real bank erosion

open access: yesJournal of Hydrology and Hydromechanics, 2019
This paper focused on predicting the bank erosion through the Bank Assessment for Non-point source Consequences of Sediment (BANCS) model on the Tŕstie water stream, located in the western Slovakia.
Allmanová Zuzana   +4 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Manifold-Regularized Feature Selector for High-Resolution Aerial Photographs Categorization

open access: yesIEEE Access
Recognizing each aerial photo with high-resolution (HR) is a useful technology in image understanding. Herein, a manifold-regularized feature selection (MRFS) is designed to acquire discriminative perceptual features that classify HR aerial images into ...
Jianrong Zhang, Xue Lin, Ye Liu
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

System Design and Control of an Apple Harvesting Robot [PDF]

open access: yesarXiv.org, 2020
Kaixiang Zhang   +4 more
semanticscholar   +1 more source

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