Results 111 to 120 of about 524,624 (282)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Performance testing of a low power consumption wireless sensor communication system integrated with an energy harvesting power source [PDF]

, 2012
This paper presents the performance testing results of a wireless sensor communication system with low power consumption integrated with a vibration energy harvesting power source.
Marsic, Vlad, Pozzi, Michele, Zhu, Meiling, Giuliano, Alessandro, Williams, Stewart W.   +4 more
core   +1 more source

Efficient and cost-effective monitoring of urban green spaces using combination of photogrammetry, LiDAR, and RTK in an iPhone-Based approach

Central European Forestry Journal
Urban green spaces (UGS) provide various ecological, cultural, aesthetic, and psychological functions contributing to public health and well-being. To ensure proper management and the optimal performance of all these functions, it is essential to closely
Výbošťok Jozef, Chudá Juliána, Skladan Michal, Singh Arunima, Tomčík Daniel, Mokroš Martin   +5 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

HARVESTING STRATEGIES IN A FISH STOCK DOMINATED BY LOW-FREQUENCY VARIABILITY: THE NORWEGIAN SPRING-SPAWNING HERRING (CLUPEA HARENGUS) [PDF]

Heavy positively autocorrelated natural fluctuations in a fisheries stock level are problematic for fisheries management, and collapses in the stock dynamics are difficult to avoid.
Enberg, Katja, Kaitala, Veijo, Jonzen, Niclas   +2 more
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Overview of Health and Safety Risks in the Process of Production and Storage of Forest Biomass for Energy Purposes—A Review

Energies
With increasing demands on the quality and quantity of produced biomass, as the main element of the knowledge-based economy, people and the issue of safety and health protection at work are coming to the fore.
Miloš Gejdoš, Martin Lieskovský
doaj   +1 more source