Results 111 to 120 of about 447,172 (311)
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Optimal Partial Harvesting Schedule for Aquaculture Operations
When growth is density dependent, partial harvest of the standing stock of cultured species (fish or shrimp) over the course of the growing season (i.e., partial harvesting) would decrease competition and thereby increase individual growth rates and ...
Leung, PingSun, Yu, Run
core
Manifold-Regularized Feature Selector for High-Resolution Aerial Photographs Categorization
Recognizing each aerial photo with high-resolution (HR) is a useful technology in image understanding. Herein, a manifold-regularized feature selection (MRFS) is designed to acquire discriminative perceptual features that classify HR aerial images into ...
Jianrong Zhang, Xue Lin, Ye Liu
doaj +1 more source
Rainwater harvesting is a common practice in several parts of the world. It can be used for very diverse purposes, such as human consumption, livestock and agricultural production, and flood control. A rainwater harvesting system is conceived when a catchment surface is connected to a storage reservoir.
Galvão, Carlos de Oliveira +2 more
openaire +2 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Accurate supercapacitor modeling for energy-harvesting wireless sensor nodes
Supercapacitors are often used in energy-harvesting wireless sensor nodes (EH-WSNs) to store harvested energy. Until now, research into the use of supercapacitors in EH-WSNs has considered them to be ideal or over-simplified, with non-ideal behavior ...
Geoff V. Merrett +7 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Bank erosion of the Tŕstie stream: BANCS model predictions vs. real bank erosion
This paper focused on predicting the bank erosion through the Bank Assessment for Non-point source Consequences of Sediment (BANCS) model on the Tŕstie water stream, located in the western Slovakia.
Allmanová Zuzana +4 more
doaj +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source

