RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Assessment of Potato Postharvest Loss in Awi and South Gondar Zones, Amhara Region, Ethiopia. [PDF]
Int J Food SciMossie BB +5 more
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Developing flexible automation for mushroom harvesting (Agaricus bisporus) : innovation report [PDF]
A framework for analysing crop processes and their suitability to automation was developed in order to address the challenges of labour costs and skills availability that UK growers face.
Rowley, James Henry
core
A Bio-Inspired Ring-Cutting and Compliant Clamping Mechanism for Selective Harvesting of Flexible-Stem Crops in Complex Terrain. [PDF]
Biomimetics (Basel)Du J +5 more
europepmc +1 more source
Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology
Advanced Engineering Materials, EarlyView.We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham +7 more
wiley +1 more source
The Impact of Canopy Position on the Biochemical, Nutritional, and Nutraceutical Quality Characteristics of Grapefruit Cultivars During Fruit Growth and Development. [PDF]
Plants (Basel)Manzoor M, Anjum MA.
europepmc +1 more source
Advanced Engineering Materials, EarlyView.This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal +2 more
wiley +1 more source
Influence of harvesting method on biomass yield and antimicrobial activity of Isochrysis galbana and Phaeodactylum tricornutum extracts. [PDF]
Biotechnol LettFreitas de Siqueira Junior E +3 more
europepmc +1 more source
Soft Mechanical‐Electrical Logic Using Liquid Metal‐Filled 3D‐Printed Architectures
Advanced Engineering Materials, EarlyView.We present 3D‐printed soft mechanical–electrical logic elements that use liquid metal–filled silicone tubes actuated by thermoplastic polyurethane/polylactic acid (TPU/PLA) architectures to produce Boolean operations. Complementary normally open and normally closed unit cells perform repeatable binary transitions and can be combined into more complex ...
Christoph Lehmann +2 more
wiley +1 more source