Results 51 to 60 of about 10,002 (224)

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic, Megan Wynalda, Montserrat C. Anguera   +2 more
wiley   +1 more source

Association of paediatric OCD with anti-thyroid antibodies and Hypovitaminosis D3 – A

Telangana Journal of Psychiatry, 2018
Hashimoto’s thyroiditis (HT), can present with depression, anxiety, mania, acute psychosis, dementia, loss of cognitive function and other symptoms.
B Anand, T Ravikanth, K Anusha, G Preeti
doaj   +1 more source

Retrospective analysis of cutaneous immune‐related adverse events following checkpoint inhibitor therapy in melanoma patients reveals increased risk associated with the HLA‐B*51:01 allele

Cancer, Volume 132, Issue 3, 1 February 2026.
ABSTRACT Background While immune checkpoint inhibitors (ICIs) have shown significant efficacy, a common side effect is cutaneous immune‐related adverse events (irAEs). This study focuses on exploring the association between specific human leukocyte antigen (HLA) alleles and the development of cutaneous irAEs in melanoma patients undergoing ICI ...
Mckenzie DiLeo, Samantha Oglesby, Cheuk Hong Leung, Kristen E. Pauken, Sahira Farooq, Lauren E. Haydu, Shelby L. Kubicki, Rebeca Martinez, Macartney Welborn, Sana Zahiruddin, Jun Zou, Kai Cao, Anisha B. Patel   +12 more
wiley   +1 more source

Understanding the Challenges of Hashimoto's Thyroiditis: Perspectives on Diagnosis, Treatment, and Associated Conditions

Journal of Education, Health and Sport
Introduction: Hashimoto's thyroiditis is a prevalent autoimmune disease among the population. With the progress in diagnostic and research techniques, it has come to light that Hashimoto's thyroiditis is linked to a higher likelihood of developing other
Klaudia Brygida Kułak, Karolina Palacz, Katarzyna Gadżała, Izabela Janik, Marzena Pliszka, Katarzyna Chamera-Cyrek, Anna Maria Koman   +6 more
doaj   +1 more source

Graves' disease following hypothyroidism due to Hashimoto's thyroiditis in a black South African lady: a case report

The Pan African Medical Journal, 2019
Graves' disease and Hashimoto's thyroiditis are autoimmune thyroid disorders with distinct pathological and histopathological features. The conversion from Hashimoto's thyroiditis to Graves' disease has been rarely reported throughout the world with no ...
Chukwuma Ekpebegh, Khaled Elmezughi, Lungiswa Mtingi   +2 more
doaj   +1 more source

New‐onset autoimmune disease following SARS‐CoV‐2 infection and mRNA vaccination in Norway: A retrospective cohort study

Journal of Internal Medicine, Volume 299, Issue 2, Page 271-282, February 2026.
Abstract Background Studies suggest an increase in autoimmune diseases following SARS‐CoV‐2 infection and/or COVID‐19‐vaccination. We aimed to describe possible associations in Norway. Methods We used information from the emergency preparedness register for COVID‐19, BeredtC19, for all residents aged 18–64 (N = 3,450,080).
Håkon Bøås, Paz Lopez‐Doriga Ruiz, Jesper Dahl, Hanne L. Gulseth, German Tapia   +4 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 1, January 2026.
ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas, Bijay Vaidya, Richard David Leslie, Daniel Agardh, Richard Oram, Dana Dabelea, Arunjot Singh, Dimitrios Chantzichristos, Marian Rewers   +8 more
wiley   +1 more source

Vitamin D supplementation in patients with Hashimoto’s disease

Journal of Education, Health and Sport
Introduction : Hashimoto’s thyroiditis (HT) is the most common autoimmune disease and the leading cause of hypothyroidism in the world. The condition results in damage to the thyroid gland, brought about by the infiltration of lymphocytes.
Amelia Kasprzak, Aleksandra Mańkowska, Monika Truchta, Agata Kolano, Wiktoria Jabłońska, Marta Wardęszkiewicz, Szymon Markowiak, Maciej Świercz, Anna Pejas   +8 more
doaj   +1 more source