Results 121 to 130 of about 5,291,425 (217)

Acute exercise‐induced improvements in cognition: Role of cerebral blood flow and metabolism

Experimental Physiology, EarlyView.
Abstract Physical activity is widely recognized for its ability to promote brain health, with acute exercise transiently enhancing cognition and long‐term training attenuating cognitive decline. However, the mechanisms underlying these benefits remain incompletely understood.
Takeshi Hashimoto, Shigehiko Ogoh
wiley   +1 more source

A case of acute lithium encephalopathy associated with elevated myelin basic protein levels in cerebrospinal fluid [PDF]

PCN Rep
Abstract Background Acute lithium intoxication can cause severe central nervous system (CNS) manifestations, sometimes leading to long‐term sequelae known as the syndrome of irreversible lithium‐effectuated neurotoxicity (SILENT). However, its underlying pathophysiology remains unclear.
Yokoyama T, Hashimoto T, Moriyama Y, Yoshino A.   +3 more
europepmc   +2 more sources

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

Experimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells

Experimental Physiology, EarlyView.
Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene, Anita M. van den Hoek, Roeland Hanemaaijer, Lars Verschuren, Jelle C. B. C. de Jong   +4 more
wiley   +1 more source

Audiovestibular Dysfunction in Patients with Hashimoto’s Disease: A Systematic Review

Although the inner ear is considered an immune-privileged organ because of the blood–labyrinth barrier, accumulating evidence has revealed an unexpected relation between Hashimoto’s disease and inner ear damage manifesting as audiovestibular ...
Tien-Yu Chen, Chih-Sung Liang, Chih-Wei Hsu, Jiann-Jy Chen, Yen-Wen Chen, Bing-Yan Zeng, Ping-Tao Tseng   +6 more
core   +1 more source

Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults

Experimental Physiology, EarlyView.
Abstract Repeated hot water immersion can improve cardiovascular health; however, the respective effects of distinct immersion protocols remain unclear. Twenty‐two healthy adults completed three 30‐min hot water immersion bouts of different water temperatures and immersion depths (40°C shoulder‐deep immersion, 40‐Shoulder; 42°C waist‐deep immersion, 42‐
Campbell Menzies, Neil D. Clarke, Charles J. Steward, Charles Douglas Thake, Christopher J. A. Pugh, Tom Cullen   +5 more
wiley   +1 more source

Human Leukocyte Antigen (HLA) Subtype-Dependent Development of Myasthenia Gravis, Type-1 Diabetes Mellitus, and Hashimoto Disease: A Case Report of Autoimmune Polyendocrine Syndrome Type 3. [PDF]

Am J Case Rep, 2019
Gobaru M, Ashida K, Yoshinobu S, Nagayama A, Kabashima M, Iwata S, Hasuzawa N, Tsuruta M, Wada N, Nakayama H, Motomura S, Tajiri Y, Nomura M.   +12 more
europepmc   +1 more source

The contribution of peripheral nerves to the pleasure from scratching an itch: Evidence from a neuronopathy participant

The Journal of Physiology, EarlyView.
Abstract figure legend Acute itch was experimentally induced using histamine and cowage in control participants (with no neuronopathy) and in IW, a participant with a large‐fibre sensory neuronopathy resulting in the loss of Aβ afferent function below C3, at the same time as largely preserving Aδ and C‐fibre function.
Adarsh D. Makdani, Andrew G. Marshall, Jonathan Cole, Francis McGlone   +3 more
wiley   +1 more source

Cancer‐associated fibroblast heterogeneity across solid and haematological malignancies: Lessons from colorectal cancer and multiple myeloma

The Journal of Physiology, EarlyView.
Abstract figure legend CAF origins and plasticity give rise to distinct phenotypes with immunosuppressive functions in colorectal cancer and multiple myeloma. These distinct CAF phenotypes contribute to immunosuppressive tumour microenvironments through ECM remodelling, cytokine signalling and immune regulation.
Hui Mo, Haoyan Han, Michael O'Dwyer, Eileen Reidy, Aideen E. Ryan   +4 more
wiley   +1 more source

Comparison of the Clinical Outcomes Between Gel Immersion and Underwater Endoscopic Mucosal Resection for Superficial Non‐ampullary Duodenal Epithelial Tumors (With Video)

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objective Gel immersion endoscopic mucosal resection (GIEMR) has recently emerged as a novel technique for superficial non‐ampullary duodenal epithelial tumors (SNADETs). However, its clinical advantages over underwater EMR (UEMR) remain unclear. This study compared the short‐ and long‐term outcomes of GIEMR and UEMR for SNADETs.
Mitsuru Otsuka, Takuto Hikichi, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Takumi Yanagita, Eisuke Kameoka, Rei Suzuki, Mitsuru Sugimoto, Hiroyuki Asama, Hiroshi Shimizu, Kento Osawa, Rei Ohira, Daiki Nemoto, Yuko Hashimoto, Masao Kobayakawa, Hiromasa Ohira   +16 more
wiley   +1 more source