Results 201 to 210 of about 28,128 (285)

Gene Regulatory Programs of NK Cells Show That NCAM1 (CD56) and KIRs Are Controlled by Genetically Polymorphic Distal Regulatory Elements

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
A deeper understanding of the natural killer cell gene expression regulation driving NK cell maturation and cytotoxicity could provide critical insights into optimizing NK therapies. Our findings reveal novel enhancers governing NK cell genes for NCAM1/CD56 and cis‐regulation for KIR receptors and clarify existing models of NK cell cis‐accessibility ...
Mariam A. Salem   +9 more
wiley   +1 more source

Reasoning‐optimised large language models reach near‐expert accuracy on board‐style orthopaedic exams: A multi‐model comparison on 702 multiple‐choice questions

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 2, Page 752-762, February 2026.
Abstract Purpose The purpose of this study was to compare the accuracy, calibration, reproducibility and operating cost of seven large language models (LLMs)—including four newer models capable of using advanced reasoning techniques to analyse complex medical information and generate accurate responses—on text‐only orthopaedic multiple‐choice questions
Pedro Diniz   +5 more
wiley   +1 more source

Stress and Rock Failure Near Salt Bodies: Insights From Field Observations, Kinematic Modeling, and Mechanical Analysis Near Arches National Park, Paradox Basin, Utah

open access: yesJournal of Geophysical Research: Solid Earth, Volume 131, Issue 2, February 2026.
Abstract Salt's inherent weakness and capacity for ductile deformation create significant mechanical contrasts that locally perturb the stress field in surrounding rocks, often leading to deviations from regional tectonic stresses. Variations in local stress are a critical factor for wellbore stability, seal integrity, and fluid flow in subsurface ...
Lauren J. Reeher   +3 more
wiley   +1 more source

Development, external validation and integration into clinical workflow of machine learning models to support pre‐operative assessment in the UK

open access: yesAnaesthesia, Volume 81, Issue 2, Page 201-212, February 2026.
Summary Introduction Demand for surgical treatment is growing and patient complexity is increasing. The NHS England standard contract now requires that pre‐operative services risk stratify and optimise patients awaiting surgery. However, current pre‐operative workflows (whether electronic or paper‐based) remain based primarily on resource‐intensive ...
Alwyn Kotzé   +7 more
wiley   +1 more source

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