Results 51 to 60 of about 28,128 (285)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

Advanced Science, EarlyView.
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia, Martin J. Graves, Mary McLean, Carolin Pirkl, Carola‐Bibiane Schönlieb, Timo Schirmer, Florian Wiesinger, Matthias J. Ehrhardt   +7 more
wiley   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Securing Generative Artificial Intelligence with Parallel Magnetic Tunnel Junction True Randomness

Advanced Intelligent Systems, EarlyView.
True random numbers can protect generative artificial intelligence (GAI) models from attacks. A highly parallel, spin‐transfer torque magnetic tunnel junction‐based system is demonstrated that generates high‐quality, energy‐efficient random numbers.
Youwei Bao, Shuhan Yang, Hyunsoo Yang
wiley   +1 more source

Density Sensitive Hashing [PDF]

IEEE Transactions on Cybernetics, 2014
Nearest neighbor search is a fundamental problem in various research fields like machine learning, data mining and pattern recognition. Recently, hashing-based approaches, for example, locality sensitive hashing (LSH), are proved to be effective for scalable high dimensional nearest neighbor search. Many hashing algorithms found their theoretic root in
Zhongming, Jin, Cheng, Li, Yue, Lin, Deng, Cai   +3 more
openaire   +2 more sources

Voxel‐SLAM: A Complete, Accurate, and Versatile Light Detection and Ranging‐Inertial Simultaneous Localization and Mapping System

Advanced Intelligent Systems, EarlyView.
: In this work, Voxel‐SLAM (simultaneous localization and mapping) is introduced: a complete, accurate, and versatile LiDAR (light detection and ranging) ‐inertial SLAM system consisting of five modules: initialization, odometry, local mapping (LM), loop closure (LC), and global mapping (GM), all employing the same map representation, an adaptive voxel
Zheng Liu, Haotian Li, Chongjian Yuan, Xiyuan Liu, Jiarong Lin, Rundong Li, Chunran Zheng, Bingyang Zhou, Wenyi Liu, Fu Zhang   +9 more
wiley   +1 more source

Performance Investigation of Eco‐Friendly Refrigerant Mixtures as an Alternative to R134a in Vapour‐Compression Refrigeration System

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The growing impacts of climate change and energy scarcity demand environmentally sustainable refrigeration solutions. This study investigates eco‐friendly refrigerants (R152a, R290 and R600a) and their optimized ternary mixture as alternatives to R134a. Four blend compositions were analysed using experimental testing and REFPROP 10.0 modelling
M. Periyasamy, P. Senthilkumar
wiley   +1 more source

Online Hashing for Scalable Remote Sensing Image Retrieval

Remote Sensing, 2018
Recently, hashing-based large-scale remote sensing (RS) image retrieval has attracted much attention. Many new hashing algorithms have been developed and successfully applied to fast RS image retrieval tasks.
Peng Li, Xiaoyu Zhang, Xiaobin Zhu, Peng Ren   +3 more
doaj   +1 more source