Results 41 to 50 of about 678,841 (321)
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Microfluidic active pressure and flow stabiliser
Scientific Reports, 2021 In microfluidics, a well-known challenge is to obtain reproducible results, often constrained by unstable pressures or flow rates. Today, there are existing stabilisers made for low-pressure microfluidics or high-pressure macrofluidics, often consisting ...
Simon Södergren +2 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Breastfeeding Benefits and Resources: Breastmilk feeds more than just babies!
EDISThis publication explains the importance of breastmilk to the infant gut microbiome. First, the gut microbiome is defined, then the source of infant microbes is introduced, and finally the role of breastfeeding in infant gut microbiome and infant health.
Diana Hazard Taft
doaj +1 more source
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2017 The California Medical Supervision program is designed to protect workers who regularly mix, load, or apply the highly toxic Category I and II organophosphates and carbamates from overexposure by monitoring cholinesterase (ChE) inhibition in plasma and ...
Ouahiba Laribi PhD +5 more
doaj +1 more source
Thermally controlled microfluidic back pressure regulator
Scientific Reports, 2022 By using the temperature dependence of viscosity, we introduce a novel type of microfluidic lab-on-a-chip back pressure regulator (BPR) that can be integrated into a micro-total-analysis-system.
Karolina Svensson +2 more
doaj +1 more source
Hazard recognition in an immersive virtual environment: Framework for the simultaneous analysis of visual search and EEG patterns [PDF]
arXiv, 2020 Unmanaged hazards in dangerous construction environments proved to be one of the main sources of injuries and accidents. Hazard recognition is crucial to achieve effective safety management and reduce injuries and fatalities in hazardous job sites.
arxiv
Quantifying treatment differences in confirmatory trials under non-proportional hazards [PDF]
, 2019 Proportional hazards are a common assumption when designing confirmatory clinical trials in oncology. With the emergence of immunotherapy and novel targeted therapies, departure from the proportional hazard assumption is not rare in nowadays clinical research.
arxiv +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Modest volcanic SO2 emissions from the Indonesian archipelago
Nature Communications, 2022 Indonesia is the country with the most active volcanoes, several of which are renowned for climate-changing eruptions. Here the authors show a rather moderate sulfur emissions budget and reinforce the idea that sulfur-rich eruptions reflect long-term ...
Philipson Bani +7 more
doaj +1 more source