Results 81 to 90 of about 678,841 (321)
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
HAZARDS ANALYSIS. RADIOLOGICAL HAZARDS [PDF]
, 1962 ABS>Doses were calculated for persons off site and in the EGCR cortrol room following the maximum credible accident (depressurization), and for the public due to normal operational stack release. The assumptions and calculations used in the study are given in detail. (D.L.C.)
openaire +2 more sources
Hazards of the Road Transportation of Hazardous Materials
System Safety: Human - Technical Facility - Environment, 2020 Abstract A lot of substances and items are transported by road, sea, rail and air every day. The biggest hazard is created by the transportation of hazardous substances with flammable, caustic or toxic properties. The hazard level increases if such substances are transported through densely populated areas.
openaire +2 more sources
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
Impact of coal mining on groundwater of Luohe Formation in Binchang mining area
International Journal of Coal Science & Technology, 2020 Groundwater of Luohe Formation is the main water source for industrial and agricultural and residential use in Binchang mining area, which is one of the key elements to water conservation coal mining.
Kui Sun +8 more
doaj +1 more source
Non-constant hazard ratios in randomized controlled trials with composite endpoints [PDF]
arXiv, 2019 The hazard ratio is routinely used as a summary measure to assess the treatment effect in clinical trials with time-to-event endpoints. It is frequently assumed as constant over time although this assumption often does not hold. When the hazard ratio deviates considerably from being constant, the average of its plausible values is not a valid measure ...
arxiv
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
Indonesian Journal on Geoscience, 2019 Guntur Volcano was in a dormant state even though its seismicity had increased on April, 2013 and August, 2013. In this study, determination of hypocentre and seismic velocity structure was conducted using seismic data from 2010 to 2014 as recorded by a ...
Ahmad Basuki +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source