Results 81 to 90 of about 1,827,651 (303)
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Characteristics and evolution of geoheritages in Mentougou District in the Xishan area, Beijing
Shuiwen dizhi gongcheng dizhiMentougou District, the core region of Xishan in Beijing, is located at the junction of Yanshan and Taihang mountains, where mountainous areas account for 98.5%. Over the long geological history, it has remained rich geoheritages.
Jinrui HE +9 more
doaj +1 more source
Community reactions to aircraft noise - Public reactions [PDF]
Population survey on reactions to aircraft noise in airport ...
Hazard, W. R.
core +1 more source
A low-disorder Metal-Oxide-Silicon double quantum dot
, 2018 One of the biggest challenges impeding the progress of Metal-Oxide-Silicon (MOS) quantum dot devices is the presence of disorder at the Si/SiO$_2$ interface which interferes with controllably confining single and few electrons.
Hazard, Thomas M. +3 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Non-constant hazard ratios in randomized controlled trials with composite endpoints [PDF]
arXiv, 2019 The hazard ratio is routinely used as a summary measure to assess the treatment effect in clinical trials with time-to-event endpoints. It is frequently assumed as constant over time although this assumption often does not hold. When the hazard ratio deviates considerably from being constant, the average of its plausible values is not a valid measure ...
arxiv
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Using mobile disaster response system in bridge management
Journal of Civil Engineering and Management, 2014 Over the years, various hydro-meteorological disasters have impacted many countries and civilians, thus decreasing the losses caused by these disasters has become important for disaster management.
Ming-Kuan Tsai, Nie-Jia Yau
doaj +1 more source
Impact of coal mining on groundwater of Luohe Formation in Binchang mining area
International Journal of Coal Science & Technology, 2020 Groundwater of Luohe Formation is the main water source for industrial and agricultural and residential use in Binchang mining area, which is one of the key elements to water conservation coal mining.
Kui Sun +8 more
doaj +1 more source