Results 241 to 250 of about 1,422,301 (347)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Hazard analysis approaches for certain small retail establishments in view of the application of their food safety management systems. [PDF]

EFSA J, 2017
EFSA Panel on Biological Hazards (BIOHAZ), Ricci A, Chemaly M, Davies R, Fernández Escámez PS, Girones R, Herman L, Lindqvist R, Nørrung B, Robertson L, Ru G, Simmons M, Skandamis P, Snary E, Speybroeck N, Ter Kuile B, Threlfall J, Wahlström H, Allende A, Barregård L, Jacxsens L, Koutsoumanis K, Sanaa M, Varzakas T, Baert K, Hempen M, Rizzi V, Van der Stede Y, Bolton D.   +28 more
europepmc   +1 more source

Consequence Analysis of LPG-Related Hazards: Ensuring Safe Transitions to Cleaner Energy [PDF]

Carolina Ardila-Suárez, J.P. Lacoursière, Gervais Soucy, Bruna Rêgo de Vasconcelos   +3 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Evaluation of an active learning module to teach hazard and risk in Hazard Analysis and Critical Control Points (HACCP) classes. [PDF]

Heliyon, 2017
Oyarzabal OA, Rowe E.
europepmc   +1 more source

Wildfire Hazards: An Analysis of Duration, Cost, and Size

, 2012
Jude Bayham, Jonathan Yoder, Bayham, Jude, Yoder, Jonathan K.   +3 more
openalex   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Probabilistic seismic and tsunami hazard analysis (PSTHA) conditioned on a mega-thrust rupture of the Cascadia Subduction Zone. [PDF]

Front Built Environ, 2017
Park H, Cox DT, Alam MS, Barbosa AR.
europepmc   +1 more source

The Time-Dependent Method for Probabilistic Fault Displacement Hazard Analysis (PFDHA-td) [PDF]

Zhou Qingyun, Xiaoxiang Yuan
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source