Results 251 to 260 of about 27,254,668 (343)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The Efficacy of COVID-19 Vaccination in Mortality Among Multi-Ethnic Long-Term Care Residents in New Zealand. [PDF]

Australas J Ageing
Cheung G, Wu T, Beyene K, Chan AHY, Jamieson H, Lyndon M, Hikaka J, Ma'u E, Meehan B, Walker X, Rivera-Rodriguez C.   +10 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Healthful and unhealthful plant-based diets and site-specific cancer risk: a systematic review and meta-analysis of observational studies. [PDF]

Eur J Nutr
Gil-Lespinard M, Iglesias-Vázquez L, Jakszyn P.   +2 more
europepmc   +1 more source

Edge based distributed framework for real time hazard detection and road safety in smart transportation. [PDF]

Sci Rep
Sahu D, Prakash S, Pandey VK, Dixit P, Yang T, Rathore RS, Wang L, Alkhrijah Y, Cengiz K.   +8 more
europepmc   +1 more source

Can unreliable auditory hazard warnings help the driver? The effect of timing errors and false alarms on road hazard detection in dynamic road scenes. [PDF]

Cogn Res Princ Implic
Song J, Wolfe B.
europepmc   +1 more source

A systematic assessment of regional landslide risk under typhoon rainfall: a case study of Taishun, Zhejiang, China in September 2016. [PDF]

Sci Rep
Xie C, Xu C, Xu X, Huang Y, Li Y, Chen K, Zheng Z, Zhang W, Wu S.   +8 more
europepmc   +1 more source