Results 141 to 150 of about 5,246,438 (234)

Hazard Assessment of Antioxidants as Contaminants of Concern. [PDF]

Environ Sci Technol Lett
Seller-Brison C, Weissbach F, Jorner K, Scheringer M, Fenner K.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

NLRP3 inflammasome activation by particles and fibers: implications for human hazard assessment. [PDF]

Arch Toxicol
Busch M, Bredeck G, Bouwmeester H, Schins RPF.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

GIS-based landslide hazard assessment: An overview

, 2005
In recent years, landslide hazard assessment has played an important role in developing land utilization regulations aimed at minimizing the loss of lives and damage to property. A variety of approaches has been used in landslide assessment and these can
Weiya Xu (2072635), Gonghui Wang (5584742), Huabin Wang (1582882), Gang-Jun Liu (18029449)   +3 more
core  

Inulin Inhibits the Inflammatory Response through Modulating Enteric Glial Cell Function in Type 2 Diabetic Mellitus Mice by Reshaping Intestinal Flora

ACS Omega, 2023
Meng-Ying Li, Jia-Qi Duan, Xiao-Hui Wang, Meng Liu, Qiao-Yi Yang, Yan Li, Kun Cheng, Han-Qiang Liu, Feng Wang   +8 more
doaj   +1 more source

Disaster mechanisms and hazard assessment of rapid and steep-gully debris flows based on FLO-2D simulation. [PDF]

PLoS One
Du H, Lai R, Zhu J.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Hazard assessment of resin-based dental monomers: directions for greener dental material development. [PDF]

Biomater Investig Dent
Alatteili MA, Abid H'EH, Elsharkawy MT, Salti ASM, Shammamah EEM, Nimir RY, Darmani H.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source