Results 181 to 190 of about 5,246,438 (234)

Health hazard assessment and cooking effects on toxic metals in marine fish from the mediterranean sea at the Damietta Coast, Egypt. [PDF]

Sci Rep
Makroum AH, Zakaria AI, Elshebrawy HA, Sallam KI.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Machine learning-based ground motion simulation for seismic hazard assessment of critical water infrastructure in Azerbaijan (Case study: Major Shamkir water reservoir). [PDF]

PLoS One
Babayev T, Babayev G, Bayramov E, Irawan S, Neafie J, Aliyeva S.   +5 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Uptake and Biotransformation Govern the Toxicity of Reactive Acrylamides in an <i>In Vivo</i> Zebrafish Embryo Model: Implications for NAM-Based Hazard Assessment. [PDF]

Environ Sci Technol
Grasse N, Scholz S, Reemtsma T, Fu Q.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Integrated Chemical and Hazard Assessment of Plastic Pellets from the <i>Toconao</i> Spill (Galicia, Spain) Indicates Potential for Environmental Harm. [PDF]

Environ Sci Technol
Morales-Caselles C, Booth AM, Baztan J, Berget LM, Carmona E, Corcoll N, Dirven H, Filella M, Gómez-Martínez D, Herzke D, Hjertholm H, Jahnke A, Jepsen PM, Kardgar AK, Lorenz C, Negi N, Rojo-Nieto E, Snapkow I, Sørensen L, Syberg K, Takada H, Turner A, Carney-Almroth B.   +22 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

A target-based approach for multi-hazard assessment: application to volcanic hazards

A target-based approach for multi-hazard assessment: application to volcanic ...
Fabrizio Meroni, Vera Pessina, Alexander Garcia, Annalisa Cappello, Laura Sandri, Elisa Varini   +5 more
core  

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment. [PDF]

Nanomaterials (Basel)
Lei P, Zegeye FD, Alswady-Hoff M, Marcolungo C, Danielsen PH, Madsen AM, Wallin H, Vogel U, Zienolddiny-Narui S, Erdem JS.   +9 more
europepmc   +1 more source