Results 191 to 200 of about 59,862 (304)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Climate-Driven Aflatoxin M₁ Risks in Serbia: Implications for Integrated Food Safety Management Along the Dairy Chain. [PDF]

Toxins (Basel)
Milićević DR, Udovički B, Šuša A, Rajković A, Pleadin J.   +4 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Re: Furrer MA, Lyttwin B, Pärli MS, et al. Incidental Prostate Cancer Is an Uncommon but Clinically Nonnegligible Cause of Death in Selected Long-term Survivors of Urothelial Carcinoma-Oncological Outcomes and a Proposed Follow-up Strategy from a Tertiary Referral Center. Eur Urol Open Sci 2026;86:10-9. [PDF]

Eur Urol Open Sci
Manikya S, Vadhithala V, Kumar R.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mars sample return campaign: biological risk and a proposed sample safety assessment protocol. [PDF]

Appl Environ Microbiol
McDonnell G, Teece BL, Mackelprang R, Cressie N, McQuiston JR, Mayhew LE, Steele A, Siljeström S, Ahern BM, Baird N, Davis RE, French KL, Glamoclija M, Graham H, Hummel KB, Page W, Pearce N, Regberg A, Relman D, Sephton MA, Sherwood Lollar B, Vanhomwegen J, Wilhelm MB, Shirey B, Beaty DW.   +24 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Precaution with standards: rethinking respiratory sensitization classification through the case of methyl methacrylate. [PDF]

Front Toxicol
Faulhammer F.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Acute Pediatric Health Risks from Elastomer Thermolysis-PAH Emission Scenarios at School Receptors Following an Industrial Tire Fire. [PDF]

Molecules
Pająk K, Reindl AR.
europepmc   +1 more source