Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Mars sample return campaign: biological risk and a proposed sample safety assessment protocol. [PDF]
McDonnell G +24 more
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The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
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Climate-Driven Aflatoxin M<sub>1</sub> Risks in Serbia: Implications for Integrated Food Safety Management Along the Dairy Chain. [PDF]
Milićević DR +4 more
europepmc +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Re: Furrer MA, Lyttwin B, Pärli MS, et al. Incidental Prostate Cancer Is an Uncommon but Clinically Nonnegligible Cause of Death in Selected Long-term Survivors of Urothelial Carcinoma-Oncological Outcomes and a Proposed Follow-up Strategy from a Tertiary Referral Center. Eur Urol Open Sci 2026;86:10-9. [PDF]
Manikya S, Vadhithala V, Kumar R.
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In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Precaution with standards: rethinking respiratory sensitization classification through the case of methyl methacrylate. [PDF]
Faulhammer F.
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The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Acute Pediatric Health Risks from Elastomer Thermolysis-PAH Emission Scenarios at School Receptors Following an Industrial Tire Fire. [PDF]
Pająk K, Reindl AR.
europepmc +1 more source

