Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Ground-motion characterization for the probabilistic seismic hazard assessment in Turkey [PDF]
This study describes the methodology implemented to establish the ground-motion logic-tree for national probabilistic seismic hazard map of Turkey for shallow active crustal regions.
AKKAR, DEDE SİNAN +3 more
core +1 more source
Characterizations of Lifetime Distributions Using Two Relative Reliability Measures
In this paper, a general characterization property considering two new dynamic relative reliability measures is obtained. The new dynamic relative reliability measures are expressed as the ratio of hazard rates and as the ratio of reversed hazard rates ...
Ghadah Alomani, Mohamed Kayid
doaj +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
Development of a novel method for cross-disciplinary hazard identification [PDF]
Hazards and risks are currently identified in generic risk silos using top-down tools and methods which are incorporated into whole system risk management frameworks such as enterprise risk management.
Parchment, Ann
core
Mass spectrometric isomer characterization of perfluorinated compounds in technical mixture, water and human blood [PDF]
Perfluorinated compounds (PFC) are special surfactants which have been used since the 1950s. Their detection in the environment started at the beginning of the 2000s.
Langlois, Ingrid
core +1 more source
Preliminary hazard assessment and site characterization of Meşelik campus area, Eskişehir-Turkey [PDF]
Limited knowledge of ground conditions, such as geotechnical parameters, is one of the main causes of foundation failure. Unknown ground conditions can also cause additional burden costs.
A. Orhan, M. Turkoz, H. Tosun
doaj +1 more source
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source

