Results 91 to 100 of about 328,314 (314)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Inferences for the Change-Point of The Exponentiated Weibull Hazard Function
Revstat Statistical Journal, 2012 In many applications of lifetime data analysis, it is important to perform inferences about the change-point of the hazard function. The change-point could be a maximum for unimodal hazard functions or a minimum for bathtub forms of hazard functions and
Josmar Mazucheli +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Simple GMM Estimator for the Semi-Parametric Mixed Proportional Hazard Model [PDF]
Ridder and Woutersen (2003) have shown that under a weak condition on the baseline hazard there exist root-N consistent estimators of the parameters in a semiparametric Mixed Proportional Hazard model with a parametric baseline hazard and unspecified ...
Ridder, Geert, Bijwaard, Govert
core
Detecting Clinical Risk Shift Through log–logistic Hazard Change-Point Model
MathematicsThe change–point problem is about identifying when a pattern or trend shifts in time–ordered data. In survival analysis, change–point detection focuses on identifying alterations in the distribution of time–to–event data, which may be subject to ...
Shobhana Selvaraj Nadar +2 more
doaj +1 more source
The Use of Hazard Models for the Analysis of Income Inequalities in Poland
Folia Oeconomica Stetinensia, 2018 The aim of the paper is to examine the income inequalities of men and women in Poland. We estimate conditional cumulative distribution functions for incomes in both groups of people using a flexible hazard-function based estimator in the presence of ...
Landmesser Joanna Małgorzata
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A rule-of-thumb for the variable bandwidth selection in kernel hazard rate estimation [PDF]
In nonparametric curve estimation the decision about the type of smoothing parameter is critical for the practical performance. The nearest neighbor bandwidth as introduced by Gefeller and Dette 1992 for censored data in survival analysis is specified by
Weißbach, Rafael, Gefeller, Olaf
core
Models of Firm Dynamics and the Hazard Rate of Exits:Reconciling Theory and Evidence using Hazard Regression Models [PDF]
, 2005 This paper considers empirical work relating to models of firm dynamics. We show that a hazard regression model for firm exits, with a modification to accommodate age-varying covariate effects, provides an empirical framework accommodating many of the ...
Bhattacharjee, Arnab +1 more
core
Profit Optimalization in Operation Systems
Polish Maritime Research, 2016 The aim of this study is to analyse the effect of reducing the number of secondary damage to profit from the work of a technical object. Considering the criterion function that describes the average profit from the work of a technical object in the ...
Knopik Leszek +2 more
doaj +1 more source