Results 111 to 120 of about 851,015 (302)

Characterizations of Distributions of Ratio of Certain Independent Random Variables [PDF]

open access: yes, 2013
Various characterizations of the distributions of the ratio of two independent gamma and exponential random variables as well as that of two independent Weibull random variables are presented.
Hamedani, Gholamhossein
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Multivariate hazard orderings of discrete random vectors [PDF]

open access: yes
The task of comparing two random vectors with respect to some multivariate stochastic ordering usually involves an infinite number of comparisons. Dyckerhoff and Mosler (1997) proved that, when the random vectors have finite supports, this task, for some
Colangelo Antonio
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Semiparametric Relative-risk Regression for Infectious Disease Data

open access: yes, 2012
This paper introduces semiparametric relative-risk regression models for infectious disease data based on contact intervals, where the contact interval from person i to person j is the time between the onset of infectiousness in i and infectious contact ...
Kenah, Eben
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

NEW DEVELOPMENTS ON THE USE OF BIVARIATE RODRIGUEZ-BURR III DISTRIBUTION IN RELIABILITY STUDIES [PDF]

open access: yes
In this paper we study the bivariate Rodriguez-Burr III distribution from a reliability point of view. In particular, we derive various functions used in reliability theory of conditional distributions, viz hazard rate, reversed hazard rate, mean ...
Filippo Domma
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Linear and Quadratic Functionals of RandomHazard rates: an Asymptotic Analysis [PDF]

open access: yes
A popular Bayesian nonparametric approach to survival analysis consists in modeling hazard rates as kernel mixtures driven by a completely random measure.
Giovanni Peccati, Igor Prünster
core  

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