On the Effect of Random Alternating Perturbations on Hazard Rates
, 2006 We consider a model for systems perturbed by dichotomous noise, in which the hazard rate function of a random lifetime is subject to additive time-alternating perturbations described by the telegraph process.
Di Crescenzo, Antonio +1 more
core +1 more source
Using weibull mixture distributions to model heterogeneous survival data [PDF]
, 2003 In this article we use Bayesian methods to fit a Weibull mixture model with an unknown number of components to possibly right censored survival data. This is done using the recently developed, birth-death MCMC algorithm.
Marín Díazaraque, Juan Miguel +2 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Estimation of the cumulative baseline hazard function for dependently right-censored failure time data. [PDF]
J Appl Stat, 2021 Wang A, Jia X, Jin Z.
europepmc +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Semi-parametric estimation of the hazard function in a model with covariate measurement error [PDF]
, 2006 We consider a model where the failure hazard function, conditional on a covariate $Z$ is given by $R(t,\theta^0|Z)=\eta\_{\gamma^0}(t)f\_{\beta^0}(Z)$, with $\theta^0=(\beta^0,\gamma^0)^\top\in \mathbb{R}^{m+p}$.
Martin-Magniette, Marie-Laure +1 more
core +3 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Linear and Quadratic Functionals of RandomHazard rates: an Asymptotic Analysis [PDF]
A popular Bayesian nonparametric approach to survival analysis consists in modeling hazard rates as kernel mixtures driven by a completely random measure.
Giovanni Peccati, Igor Prünster
core
The Kumaraswamy Marshal-Olkin Family of Distributions [PDF]
, 2015 We introduce a new family of continuous distributions called the Kumaraswamy Marshal-Olkin generalized family of distributions. We study some mathematical properties of this family.
Alizadeh, Morad +5 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source