Results 41 to 50 of about 327,364 (268)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

MODELING STRENGTH OF THE AIRCRAFT WINDOW GLASS BY TRUNCATED SHAMBHU DISTRIBUTION

Reliability: Theory & Applications
Failure of regular distributions to appropriately model the real life scenarios demands the new distributions, which will be more useful. Truncated distributions are found to model many real datasets more precisely than corresponding regular ...
Dhanashri Patil, Manjushri Chikkalli, Shruti Hipale, Chandrakant Gardi   +3 more
doaj   +1 more source

Odd Generalized Rayleigh- Exponential distribution Statistical Properties with Real Data Application [PDF]

Kirkuk Journal of Science
In this paper we offer a new distribution due to the most common problem for researchers is to determine a statistical model for analyzing lifetime data.
ِAli Monef
doaj   +1 more source

Oscillation and hazard functions

Mathematical and Computer Modelling, 2000
In the medical data analysis, the shapes of hazard functions are very important for the survival analysis. The simple dimensional hazard function is given by r(t) = f(t)(1 - F(t)), 0 @? F(t) < 1, where f(t) is a probability density function with its distribution function F(t).
openaire   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Inferences for the Change-Point of The Exponentiated Weibull Hazard Function

Revstat Statistical Journal, 2012
In many applications of lifetime data analysis, it is important to perform inferences about the change-point of the hazard function. The change-point could be a maximum for unimodal hazard functions or a minimum for bathtub forms of hazard functions and
Josmar Mazucheli , Emílio Augusto Coelho-Barros   +1 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Detecting Clinical Risk Shift Through log–logistic Hazard Change-Point Model

Mathematics
The change–point problem is about identifying when a pattern or trend shifts in time–ordered data. In survival analysis, change–point detection focuses on identifying alterations in the distribution of time–to–event data, which may be subject to ...
Shobhana Selvaraj Nadar, Vasudha Upadhyay, Savitri Joshi   +2 more
doaj   +1 more source