Results 101 to 110 of about 3,726,940 (286)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Hazard identification, risk assessment and risk control (HIRARC) in a corrugated box manufacturer / Fraziel Barahim [PDF]

, 2010
Packaging is one of the biggest industries in the world. It involves paper, glass,metal, flexible and plastic. The corrugated paper packaging worldwide has been growing at 3% to 4% per annum.
Barahim, Fraziel
core  

Ferrocene‐Functionalized Black Phosphorus Nanoplatform Enables Targeted and Prolonged MRI Visualization of Atherosclerotic Plaques

Advanced Science
Despite the critical role of contrast‐enhanced magnetic resonance imaging (MRI) in clinical diagnostics, current contrast agents face dual challenges: metallic formulations provoke biosafety concerns while organic radicals exhibit transient imaging ...
Xiao Huang, Yuanyuan Zhao, Miao Zhou, Yukang Guo, Haiyun Wang, Yuanyuan Chen, Jian Peng   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Neurotoxic Effects of Nanoplastics: Current Evidence and Mechanistic Insights

Toxics
Plastic products are extensively utilized in various industrial goods and consumer items. However, when these plastics fail to undergo complete degradation, they generate nanoplastic particles (NPs).
Fuxin Wan, Xiaohan Liu, Jiayue Pan, Linping Ke, Zhekai Zheng, Jingling Liao   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effectiveness of large language model-based teaching interventions in medical education: a systematic review and stratified meta-analysis of 14 studies

BMC Medical Education
Background In recent years, artificial intelligence has been adopted as an innovative educational approach and may substantially reshape health-care delivery systems. This systematic review and stratified meta-analysis compared large language model (LLM)-
Xiaoliu Liu, Jiayue Pan, Chengyi Zhang, Xiaomei Wang, Jinghua Wan, Qiang Wang   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Invited Perspective: Good Measure-Assessing the Impact of Cancer Hazard Identification on Policies for Cancer Prevention. [PDF]

Environ Health Perspect, 2023
Schubauer-Berigan MK.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source