Results 131 to 140 of about 3,726,940 (286)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

An ontological approach to hazard identification for safety-critical systems

open access: yes, 2017
Hazard identification is an essential but very de- manding task for the development of safety-critical systems (SCSs). Current practices suffer from one or several drawbacks listed below: 1) a common hazard conceptualization is missing and thereby ...
Luciana Provenzano   +7 more
core   +1 more source

From hazard identification to risk assessment: The role of the prevention technician in the carcinogenic risk assessment for formaldehyde. [PDF]

open access: yesFront Public Health, 2023
Pattavina F   +6 more
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Developmental dyslexia genes are selectively targeted by diverse environmental pollutants

open access: yesBMC Psychiatry
Background Developmental dyslexia, a complex neurodevelopmental disorder, not only affects children’s academic performance but is also associated with increased healthcare costs, lower employment rates, and reduced productivity.
Yangyang Yang   +7 more
doaj   +1 more source

Firefighting and Cancer: A Meta-analysis of Cohort Studies in the Context of Cancer Hazard Identification. [PDF]

open access: yesSaf Health Work, 2023
DeBono NL   +15 more
europepmc   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

open access: yesFEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Bacterial hazard identification and exposure assessment of raw milk consumption in Jimma zone, South West Ethiopia. [PDF]

open access: yesBMC Microbiol, 2023
Gume B   +6 more
europepmc   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

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